Document Detail


Two new isomers of domoic acid from a red alga, Chondria armata.
MedLine Citation:
PMID:  9080577     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Isodomoic acids G and H, two new isomers of the neurotoxin domoic acid, along with isodomoic acids A, B, E and F, were isolated from a red alga, Chondria armata, collected at the southern tip of Kyushu Island. The structures of two of these were deduced to be (E, E) and (Z, E) isomers of 2-carboxy-4-(5-carboxy-l-methyl-2-hexenylidene)-3-pyrro- lidineacetic acid, based on electrospray ionization mass and [1H]nuclear magnetic resonance spectral analyses including [1H-1H]correlation spectroscopy and nuclear Overhauser effect correlation spectroscopy.
Authors:
L Zaman; O Arakawa; A Shimosu; Y Onoue; S Nishio; Y Shida; T Noguchi
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Toxicon : official journal of the International Society on Toxinology     Volume:  35     ISSN:  0041-0101     ISO Abbreviation:  Toxicon     Publication Date:  1997 Feb 
Date Detail:
Created Date:  1997-06-05     Completed Date:  1997-06-05     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  1307333     Medline TA:  Toxicon     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  205-12     Citation Subset:  IM    
Affiliation:
Laboratory of Marine Botany and Environmental Science, Faculty of Fisheries, Kagoshima University, Japan.
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MeSH Terms
Descriptor/Qualifier:
Algae, Red*
Chromatography, High Pressure Liquid
Isomerism
Kainic Acid / analogs & derivatives*,  analysis,  chemistry,  isolation & purification
Magnetic Resonance Spectroscopy
Mass Spectrometry
Molecular Structure
Neuromuscular Depolarizing Agents / analysis,  chemistry,  isolation & purification*
Chemical
Reg. No./Substance:
0/Neuromuscular Depolarizing Agents; 14277-97-5/domoic acid; 487-79-6/Kainic Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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