Document Detail


Two new antifungal cyclic lipopeptides from Bacillus marinus B-9987.
MedLine Citation:
PMID:  21139268     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Two new cyclic lipopeptides maribasins A (1) and B (2) were isolated from the fermentation broth of the marine microorganism Bacillus marinus B-9987 isolated from Suaeda salsa in Bohai coastline of P. R. China. Both structures were established to be cyclo (D-Pro-L-Gln-L-Asn-L-Ser-D-Asn¹-D-Tyr-D-Asn²-D-β-aminoisopentadecanoic acid) (1) and cyclo (D-Pro-L-Gln-L-Asn-L-Ser-D-Asn¹-D-Tyr-D-Asn²-D-β-aminoanteisopentadecanoic acid) (2) by spectroscopic analysis and exhibited broad-spectrum activity against phytopathogens by the antifungal bioassay.
Authors:
Dao-Jing Zhang; Rong-Feng Liu; Yuan-Guang Li; Li-Ming Tao; Li Tian
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Chemical & pharmaceutical bulletin     Volume:  58     ISSN:  1347-5223     ISO Abbreviation:  Chem. Pharm. Bull.     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2010-12-08     Completed Date:  2011-03-24     Revised Date:  2012-10-09    
Medline Journal Info:
Nlm Unique ID:  0377775     Medline TA:  Chem Pharm Bull (Tokyo)     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  1630-4     Citation Subset:  IM    
Affiliation:
State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, PR China.
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MeSH Terms
Descriptor/Qualifier:
Amino Acid Sequence
Antifungal Agents / chemistry*,  isolation & purification,  pharmacology
Bacillus / metabolism*
Lipopeptides / chemistry*,  isolation & purification,  pharmacology
Magnetic Resonance Spectroscopy
Microbial Sensitivity Tests
Molecular Conformation
Peptides, Cyclic / chemistry*,  isolation & purification,  pharmacology
Chemical
Reg. No./Substance:
0/Antifungal Agents; 0/Lipopeptides; 0/Peptides, Cyclic; 0/maribasin A; 0/maribasin B

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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