Document Detail


Two new 20α(H)-ursane-type triterpenoids from Ilex cornuta and their cytotoxic activities.
MedLine Citation:
PMID:  24215489     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Two new 20α-ursane-type triterpenoids (1-2) were isolated from the roots of Ilex cornuta, along with three known triterpenoids (3-5). The structures of compounds 1-2 were determined as 3β, 23-dihydroxy-20α(H)-urs-12-en-28-oic acid (1), 3β,19α,23-trihydroxy-20α(H)-urs-12-en-28-oic acid 3β-O-α-l-arabinopyranoside (2), on the basis of hydrolysis and spectral evidence, including 1D- and 2D-NMR and high-resolution electrospray ionization mass spectrometry analyses. These pure isolates (1-5) were tested for their cytotoxic activities by MTT assay.
Authors:
Wen-Lian Wang; Xi Zhou; Yan-Li Liu; Qiong-Ming Xu; Xiao-Ran Li; Shi-Lin Yang
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-11-11
Journal Detail:
Title:  Journal of Asian natural products research     Volume:  -     ISSN:  1477-2213     ISO Abbreviation:  J Asian Nat Prod Res     Publication Date:  2013 Nov 
Date Detail:
Created Date:  2013-11-12     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100888334     Medline TA:  J Asian Nat Prod Res     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
a College of Pharmaceutical Science, Soochow University , Suzhou , 215123 , China.
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