Document Detail


Two male patients with nevoid basal cell carcinoma syndrome from Turkey.
MedLine Citation:
PMID:  11765170     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Nevoid basal cell carcinoma syndrome, also known as Gorlin's syndrome, is a familial autosomal dominant syndrome characterized by multiple basal cell carcinomas, multiple odontogenic keratocysts of the jaws, and skeletal anomalies. Both tumors and malformations of the central nervous system occur with nevoid basal cell carcinoma. Medulloblastoma is the primary brain tumor most frequently associated with this syndrome. The authors report in this article two male patients with nevoid basal cell carcinoma syndrome: a 22-year-old male patient with multiple odontogenic keratocysts, who had medulloblastoma at two years and multiple basal cell carcinoma at 10 years of age, and a 15-year-old male patient with skeletal abnormalities and multiple odontogenic keratocysts in the jaws.
Authors:
C Tümer; N Er; S Balci; A Ataç
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Turkish journal of pediatrics     Volume:  43     ISSN:  0041-4301     ISO Abbreviation:  Turk. J. Pediatr.     Publication Date:    2001 Oct-Dec
Date Detail:
Created Date:  2001-12-17     Completed Date:  2002-01-11     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0417505     Medline TA:  Turk J Pediatr     Country:  Turkey    
Other Details:
Languages:  eng     Pagination:  351-5     Citation Subset:  IM    
Affiliation:
Department of Oral Surgery, Faculty of Dentistry, Hacettepe University, Ankara, Turkey.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Basal Cell Nevus Syndrome / diagnosis*,  genetics,  pathology,  radiography
Cerebellar Neoplasms / complications*
Humans
Jaw Cysts / diagnosis*,  genetics,  pathology,  radiography
Male
Medulloblastoma / complications*
Skin Neoplasms / diagnosis*,  genetics,  pathology

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