| Two icodextrin exchanges per day in peritoneal dialysis patients with ultrafiltration failure: one center's experience and review of the literature. | |
| | |
MedLine Citation:
|
PMID: 20953705 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
BACKGROUND: At present, only one exchange of an icodextrin-based solution is recommended to increase peritoneal ultrafiltration (UF) during long-dwell exchanges in peritoneal dialysis (PD) patients with impaired UF. AIM: To review our experience with two icodextrin exchanges per day on net UF and body weight in PD patients with poor UF. METHODS: Data were analyzed on nine patients with poor UF on chronic PD who were given two icodextrin exchanges per day for 6 months and had various clinical and biochemical parameters assessed monthly. RESULTS: Administration of icodextrin twice daily reduced the body weight in six of nine patients by an average of 2.9 ± 1.2 kg, a reduction that was maintained throughout the study; two patients gained 0.5 kg; and, in one patient, the measurements were inadequate. Mean blood pressure was reduced. Mean serum creatinine increased slightly. Serum sodium levels decreased from a mean baseline level of 134 ± 3 to 132 ± 4 mmol/L at three and six months. Among the diabetics in this group, average daily insulin requirements were 44 ± 35 units/day at baseline and 40 ± 23 units/day after 6 months. Hb1Ac levels remained stable throughout the study period. CONCLUSION: The use of two icodextrin exchanges per day reduced body weight in six of the nine patients and appeared to be safe. Long-term prospective studies are needed to assess the contribution of twice-daily icodextrin to the management of peritoneal dialysis patients with ultrafiltration failure and its long-term safety. |
| | |
Authors:
|
Periklis Dousdampanis; Konstantza Trigka; Maggie Chu; Saimah Khan; Daniele Venturoli; Dimitrios G Oreopoulos; Joanne M Bargman |
Related Documents
:
|
12774455 - Positive washing cytology in patients with pancreatic cancer indicates a contraindicati... 1680425 - Peritonitis rates for capd patients using the scd 210 (inpersol sterile connecting devi... 6828945 - An interracial study of continuous ambulatory peritoneal dialysis (capd) in natal. 15471665 - Computed tomography findings of peritoneal tuberculosis: systematic review of seven pat... 21895935 - Diagnosis of isolated high-grade prostatic intra-epithelial neoplasia: proposal of a no... 18095805 - Symptoms in advanced renal disease: a cross-sectional survey of symptom prevalence in s... |
Publication Detail:
|
Type: Journal Article Date: 2010-02-21 |
Journal Detail:
|
Title: International urology and nephrology Volume: 43 ISSN: 1573-2584 ISO Abbreviation: Int Urol Nephrol Publication Date: 2011 Mar |
Date Detail:
|
Created Date: 2011-03-22 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0262521 Medline TA: Int Urol Nephrol Country: Netherlands |
Other Details:
|
Languages: eng Pagination: 203-9 Citation Subset: IM |
Affiliation:
|
University of Toronto, Toronto General Hospital, 200 Elizabeth Street, 8N-840, Toronto, ON, M5G 2C4, Canada. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Fanconi syndrome following honeybee stings.
Next Document: Incidence and risk factors for lymphoma in a single-center inflammatory bowel disease population.