Document Detail

Two genotypes of H1N2 swine influenza viruses appeared among pigs in China.
MedLine Citation:
PMID:  19632889     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: H1N2 is one of the main subtypes of influenza, which circulates in swine all over the world. OBJECTIVES: To investigate the prevalence and genetic of H1N2 in swine of China. STUDY DESIGN: Two H1N2 swine influenza viruses were isolated from Tianjin and Guangdong province of China in 2004 and 2006, respectively. The molecular evolution of eight gene segments was analyzed. RESULT: A/Swine/Tianjin/1/2004 has low identity with A/Swine/Guangdong/2006; in the phylogenetic tree of PA gene, A/Swine/Guangdong/1/2006 and A/Swine/Guangxi/1/2006 along with the H1N2 swine isolates of North America formed a cluster; and A/Swine/Tianjin/2004 and A/Swine/Zhejiang/2004, along with the classical H1N1 swine isolates formed another cluster; except that NA gene of A/Swine/Tianjin/1/2004 fell into the cluster of the H3N2 human influenza virus, indicating the reassortment between H3N2 human and H1N1 swine influenza viruses. CONCLUSION: Two different genotypes of H1N2 appeared among pigs in China. A/swine/Guangdong/1/06 was probably from H1N2 swine influenza viruses of North America; while A/swine/Tianjin/1/04 maybe come from reassortments of classical H1N1 swine and H3N2 human viruses prevalent in North America.
Chuantian Xu; Qiyun Zhu; Huanliang Yang; Xiumei Zhang; Chuanling Qiao; Yan Chen; Xiaoguang Xin; Hualan Chen
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2009-07-25
Journal Detail:
Title:  Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology     Volume:  46     ISSN:  1873-5967     ISO Abbreviation:  J. Clin. Virol.     Publication Date:  2009 Oct 
Date Detail:
Created Date:  2009-09-07     Completed Date:  2009-12-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9815671     Medline TA:  J Clin Virol     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  192-5     Citation Subset:  IM    
Animal Influenza Laboratory of the Ministry of Agriculture and National Key Laborattory of Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People's Republic of China.
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MeSH Terms
Cross-Sectional Studies
Evolution, Molecular
Influenza A Virus, H1N2 Subtype / genetics*
Nasal Cavity / virology
Orthomyxoviridae Infections / veterinary*,  virology
Swine Diseases / virology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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