Document Detail


Two-faced haemophagocytic lymphohistiocytosis: comparative review of two cases of adult haemophagocytic lymphohistiocytosis.
MedLine Citation:
PMID:  24528817     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Haemophagocytic lymphohistiocytosis (HLH) is a rare but potentially fatal disease of children and adults. Cytokine dysfunction, uncontrolled accumulation of activated T-cells and histiocytes, and the inability to terminate the immune response lead to the clinical manifestations of extreme inflammation and end-organ damage. HLH is notoriously underreported because of its ability to mimic many other common diseases. Here, we outline two cases of HLH, one primary and the other secondary, to highlight some of the differences and to discuss therapeutic principles and emerging concepts.
Authors:
E Mayson; J Saverimuttu; P Warburton
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Internal medicine journal     Volume:  44     ISSN:  1445-5994     ISO Abbreviation:  Intern Med J     Publication Date:  2014 Feb 
Date Detail:
Created Date:  2014-02-17     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101092952     Medline TA:  Intern Med J     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  198-201     Citation Subset:  IM    
Copyright Information:
© 2014 The Authors; Internal Medicine Journal © 2014 Royal Australasian College of Physicians.
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