Document Detail


Two-dimensional ultrasonic tissue characterization: backscatter power, endocardial wall motion, and their phase relationship for normal, ischemic, and infarcted myocardium.
MedLine Citation:
PMID:  3652424     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
To understand the possible differences in reflected ultrasonic energy from normal, ischemic, and infarcted myocardium, we studied 20 open-chest dogs with a commercially available two-dimensional ultrasonic scanner. Echocardiographic radiofrequency images of anterior myocardium were obtained serially during complete coronary occlusion for 2 hr (n = 15) or 5 hr (n = 10), or after temporary coronary clamping for 15 min with release for 1 hr (n = 5). We investigated two variables: the cyclic backscatter power and the phase difference among endocardial wall motion (EWM), cyclic backscatter power (BSP), and left ventricular pressure (LVP). The cyclic BSP decreased from a control (nonischemic) level of 5.1 +/- 0.8 to 2.3 +/- 0.7 dB during ischemia (up to 30 min after coronary ligation). The phase difference between the EWM and BSP progressed from a control (nonischemic) value of 38 +/- 20 to 115 +/- 23 degrees during ischemia. For the infarction period (2 to 5 hr after coronary ligation), the cyclic BSP progressively returned toward baseline control levels to 4.0 +/- 1.2 dB, but the phase had increased further to 170 +/- 28 degrees. The reperfusion study showed a similar decrease in cyclic BSP and an increase in phase after arterial clamping and both returned to near-normal nonischemic values upon arterial release. Simultaneous LVP recordings were performed to assess the phase contribution of endocardial dyskinesis to the total phase difference measurement. At 5 hr the dyskinesis had contributed 46% to the total phase difference, while the backscatter power contributed 54%. However, the EWM contribution occurred immediately while BSP contribution changed progressively during the 5 hr study period.(ABSTRACT TRUNCATED AT 250 WORDS)
Authors:
P J Fitzgerald; M D McDaniel; E L Rolett; J W Strohbehn; D H James
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Circulation     Volume:  76     ISSN:  0009-7322     ISO Abbreviation:  Circulation     Publication Date:  1987 Oct 
Date Detail:
Created Date:  1987-11-19     Completed Date:  1987-11-19     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0147763     Medline TA:  Circulation     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  850-9     Citation Subset:  AIM; IM    
Affiliation:
Cardiology Section, Dartmouth-Hitchcock Medical Center, Dartmouth Medical School, Hanover, NH.
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MeSH Terms
Descriptor/Qualifier:
Animals
Coronary Circulation
Coronary Disease / diagnosis*,  pathology,  physiopathology
Dogs
Echocardiography* / methods
Myocardial Contraction*
Myocardial Infarction / diagnosis*,  pathology,  physiopathology
Myocardium / ultrastructure

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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