| Two-dimensional graphic analysis of DNA sequence homologies. | |
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MedLine Citation:
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PMID: 7063405 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We describe a computer program designed to facilitate the pattern matching analysis of homologies between DNA sequences. It takes advantage of a two-dimensional plot in order to simplify the evaluation of significant structures inherited in the sequences. The program can be divided into three parts, i) algorithm for search of homologies, ii) two-dimensional graphic display of the result, iii) further graphic treatment to enhance significant structures. The power of the graphic display is presented by the following application of the program. We conducted a search for direct repeats in the mouse immunoglobulin kappa-chain genes. Both the five J DNA sequences and other shorter repeats were found. We also found a longer stretch of homology that could indicate the presence of duplicated DNA in the J4, J5 region. |
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Authors:
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R Harr; P Hagblom; P Gustafsson |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Nucleic acids research Volume: 10 ISSN: 0305-1048 ISO Abbreviation: Nucleic Acids Res. Publication Date: 1982 Jan |
Date Detail:
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Created Date: 1982-05-21 Completed Date: 1982-05-21 Revised Date: 2009-11-18 |
Medline Journal Info:
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Nlm Unique ID: 0411011 Medline TA: Nucleic Acids Res Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 365-74 Citation Subset: IM |
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| MeSH Terms | |
Descriptor/Qualifier:
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Base Sequence* Computers* DNA* Methods |
| Chemical | |
Reg. No./Substance:
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9007-49-2/DNA |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
| Full Text | |
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Journal Information Journal ID (nlm-ta): Nucleic Acids Res ISSN: 0305-1048 ISSN: 1362-4962 |
Article Information Download PDF  Print publication date: Day: 11 Month: 1 Year: 1982 Volume: 10 Issue: 1 First Page: 365 Last Page: 374 ID: 326139 PubMed Id: 7063405 |
| Two-dimensional graphic analysis of DNA sequence homologies. | |
| R Harr | |
| P Hagblom | |
| P Gustafsson | |
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