Document Detail

Two-dimensional Doppler echocardiographic correlation of dipyridamole-thallium stress testing with isometric handgrip.
MedLine Citation:
PMID:  2017969     Owner:  NLM     Status:  MEDLINE    
To determine how frequently new wall-motion abnormalities that are indicative of ischemia accompany thallium redistribution, 47 consecutive patients underwent two-dimensional echocardiography during routine dipyridamole-thallium stress testing. A secondary aim of the study was to determine whether the addition of isometric handgrip exercises to the standard dipyridamole imaging protocol increased the frequency of wall-motion abnormalities or thallium redistribution. Echocardiograms and thallium scans were independently interpreted, and wall-motion abnormalities that appeared with dipyridamole, handgrip exercise, or both were compared with results of thallium imaging. Five of 24 patients with thallium redistribution had new wall-motion abnormalities, and the extent (number of segments) of thallium redistribution in these five patients was significantly greater than in those who did not have well-motion abnormalities (p less than 0.03). The addition of isometric handgrip exercises to the imaging protocol did not distinguish between patients with and without new wall-motion abnormalities or thallium redistribution. Thus new wall-motion abnormalities infrequently accompany thallium redistribution in routine dipyridamole stress testing in spite of the addition of handgrip exercises, but when new wall-motion abnormalities are present, they are associated with a greater area of thallium redistribution.
S Whitfield; G Aurigemma; L Pape; J Leppo
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  American heart journal     Volume:  121     ISSN:  0002-8703     ISO Abbreviation:  Am. Heart J.     Publication Date:  1991 May 
Date Detail:
Created Date:  1991-05-23     Completed Date:  1991-05-23     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0370465     Medline TA:  Am Heart J     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1367-73     Citation Subset:  AIM; IM; S    
Department of Medicine, University of Massachussetts Medical Center, Worcester 01655.
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MeSH Terms
Coronary Disease / diagnosis*
Dipyridamole / diagnostic use*
Echocardiography, Doppler*
Evaluation Studies as Topic
Exercise Test / methods*
Heart / radionuclide imaging*
Middle Aged
Myocardial Contraction / physiology
Thallium Radioisotopes / diagnostic use
Grant Support
Reg. No./Substance:
0/Thallium Radioisotopes; 58-32-2/Dipyridamole

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