| Two different low birth weight formulae compared. | |
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MedLine Citation:
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PMID: 1396287 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The performance of two different, commercially available, low birth weight formulae feeds was compared in preterm infants. The aim of the study was to determine the effect of compositional differences on tolerance, stool frequency and consistency, fat balance and weight gain. Inborn infants with birth weight less than 1500 g were randomised at birth to receive Prematil or Osterprem. Thirty infants received more than 900 ml/kg per week of designated formula alone during a total of 70 weeks of study. Three day fat balance was performed on 23 infants. Osterprem contains 40% more fat than Prematil. The composition of this fat is different in that Osterprem contains no medium chain triglycerides (MCT) compared to 30% in Prematil. Clinical evaluation demonstrated that Osterprem is associated with a significantly higher mean energy intake compared to Prematil (3442 and 3127 kJ/kg per week) but mean weight gain is not significantly different (123 and 112 g/kg per week). Mean stool frequency is higher on Osterprem (20.5 and 14.5 stool/week) and the consistency of stools firmer. This is attributable to a higher mean fat output (2.3 and 0.9 g/kg per day) secondary to the higher fat content of the feed and lower mean absorption (71.6 and 83.5%). Both feeds are well tolerated. The study also confirms that absorption of unsaturated fatty acids is inversely proportional to chain length. |
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Authors:
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S A Spencer; S McKenna; J Stammers; D Hull |
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Publication Detail:
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Type: Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Early human development Volume: 30 ISSN: 0378-3782 ISO Abbreviation: Early Hum. Dev. Publication Date: 1992 Aug |
Date Detail:
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Created Date: 1992-10-29 Completed Date: 1992-10-29 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7708381 Medline TA: Early Hum Dev Country: NETHERLANDS |
Other Details:
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Languages: eng Pagination: 21-31 Citation Subset: IM |
Affiliation:
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North Staffordshire Maternity Hospital, Harpfields, Stoke-on-Trent, UK. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Dietary Fats
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administration & dosage* Fats / chemistry Feces Humans Infant Food* / analysis Infant, Low Birth Weight* Infant, Newborn Triglycerides / administration & dosage*, chemistry Weight Gain |
| Chemical | |
Reg. No./Substance:
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0/Dietary Fats; 0/Fats; 0/Triglycerides |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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