| Two cases of toxic anterior segment syndrome from generic trypan blue. | |
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MedLine Citation:
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PMID: 21111323 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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We report 2 cases of toxic anterior segment syndrome (TASS) resulting from impurities in generic trypan blue that was administered intracamerally to improve visualization of the capsule. Histology of the corneal buttons revealed foci of inflammatory response and complete loss of endothelial cells. Cell culture analysis showed that the generic trypan blue was approximately twice as toxic to the endothelium as a proprietary trypan blue. Ophthalmologists should be aware that any substance administered intraocularly can be a source of complications, and they should know the source of all material used in surgery. FINANCIAL DISCLOSURE: No author has a financial or proprietary interest in any material or method mentioned. |
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Authors:
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Kurt Buzard; Jue-Rong Zhang; Gabriella Thumann; Renata Stripecke; Murad Sunalp |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of cataract and refractive surgery Volume: 36 ISSN: 1873-4502 ISO Abbreviation: J Cataract Refract Surg Publication Date: 2010 Dec |
Date Detail:
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Created Date: 2010-11-29 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8604171 Medline TA: J Cataract Refract Surg Country: United States |
Other Details:
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Languages: eng Pagination: 2195-9 Citation Subset: IM |
Copyright Information:
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Copyright © 2010 ASCRS and ESCRS. Published by Elsevier Inc. All rights reserved. |
Affiliation:
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From University of Nevada (Buzard), Las Vegas, Nevada; Tulare Regional Medical Center (Zhang), Tulare, Sunalp Laser Vision and Berkeley School of Optometry (Sunalp), University of California, Berkeley, California; Departments of Vitreoretinal Surgery and Anatomy (Thuman), University of Cologne, Cologne, and Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School (Stripecke), Hannover, Germany. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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