| Two cases of synovitis, acne, pustulosis, osteitis--SAPHO syndrome. | |
MedLine Citation:
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PMID: 17684587 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Synovitis, acne, pustulosis, osteitis (SAPHO) syndrome is rare with yet unknown prevalence. The difficulty in recognizing the syndrome is due to the very wide diversity of its signs and symptoms, the lack of skin manifestations in many cases and to confusion in medical terminology in describing this syndrome. In this paper, we present two cases with characteristic bone lesions in bone scan and in radiology images that are considered to be SAPHO syndrome. In the first case the characteristic bone single photon emission tomography scan findings in a patient with spine involvement supposed by bone biopsy but were not followed by characteristic skin manifestations. The point of interest of this case lies on the significant improvement of both symptoms and scintigraphic findings after treatment with biphosphonates. In the second case the diagnosis was also based on the characteristic bone scan findings, although the patient referred to us for staging of prostate cancer. Detailed history and clinical examination revealed skin manifestations of the syndrome. |
Authors:
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Trifon Spyridonidis; Costas Giannakenas; Nikos Papandrianos; Panagiota Barla; Dimitris J Apostolopoulos |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Hellenic journal of nuclear medicine Volume: 10 ISSN: 1790-5427 ISO Abbreviation: Hell J Nucl Med Publication Date: 2007 May-Aug |
Date Detail:
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Created Date: 2007-08-08 Completed Date: 2007-11-07 Revised Date: 2010-08-23 |
Medline Journal Info:
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Nlm Unique ID: 101257471 Medline TA: Hell J Nucl Med Country: Greece |
Other Details:
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Languages: eng Pagination: 109-12 Citation Subset: IM |
Affiliation:
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University of Patras, Medical School, Department of Nuclear Medicine, Regional University Hospital of Patras, Rion, Patras 26500, Greece. tspyr@med.upatras.gr |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Acne Vulgaris
/
complications,
diagnosis* Acquired Hyperostosis Syndrome / diagnosis* Adult Aged, 80 and over Biopsy Bone Diseases / pathology Bone and Bones / pathology Humans Male Osteitis / complications, diagnosis* Prostatic Neoplasms / complications Radionuclide Imaging / methods Synovitis / complications, diagnosis* Tomography, X-Ray Computed / methods Whole Body Imaging |
| Comments/Corrections | |
Comment In:
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Hell J Nucl Med. 2010 Jan-Apr;13(1):73-5
[PMID:
20411180
]
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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