| Two cases of severe hypoalbuminemia (<10 g/L). | |
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MedLine Citation:
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PMID: 19487103 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: Hypoalbuminemia is known to occur in critically ill patients and is associated with increased mortality. Severe hypoalbuminemia is defined in the literature as serum albumin levels lower than 24 g/L. METHODS: Albumin levels were measured in our laboratory using the bromocresol purple method on the Synchron CX9 (Beckman Coulter); the lower detection limit on this apparatus is 10 g/L. RESULTS: We report two cases of severe hypoalbuminemia with levels lower than 10 g/L-one in a complete paraplegic patient with severe pressure ulcers and the other in a patient positive for the human immunodeficiency virus with chronic renal failure. CONCLUSION: Although cases of severe hypoalbuminemia (<10 g/L) are very rare in the literature, chemical pathologists should be aware of the causes of serum albumin levels of this magnitude. These cases describe two different disease states that lead to severe hypoalbuminemia by means of a similar underlying cause, namely severe inflammation or infection. |
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Authors:
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Annalise E Zemlin; Lesley J Burgess; Andries Engelbrecht |
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Publication Detail:
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Type: Case Reports; Journal Article Date: 2009-05-31 |
Journal Detail:
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Title: Nutrition (Burbank, Los Angeles County, Calif.) Volume: 25 ISSN: 1873-1244 ISO Abbreviation: - Publication Date: 2009 Oct |
Date Detail:
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Created Date: 2009-09-04 Completed Date: 2009-09-24 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8802712 Medline TA: Nutrition Country: United States |
Other Details:
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Languages: eng Pagination: 1006-10 Citation Subset: IM |
Affiliation:
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Department of Chemical Pathology, National Health Laboratory Service, Tygerberg Hospital, Stellenbosch University, Parow, South Africa. azemlin@sun.ac.za |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Anemia / complications Blood Protein Electrophoresis Bromcresol Purple Female HIV Infections / complications Humans Hypoalbuminemia / etiology*, mortality Indicators and Reagents Kidney Failure / complications Male Nephelometry and Turbidimetry Pressure Ulcer / complications Serum Albumin / analysis Spectrophotometry |
| Chemical | |
Reg. No./Substance:
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0/Indicators and Reagents; 0/Serum Albumin; 115-40-2/Bromcresol Purple |
| Comments/Corrections | |
Comment In:
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Nutrition. 2009 Oct;25(10):1004-5
[PMID:
19500943
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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