Document Detail

Two cases of right ventricular ischemic injury due to massive pulmonary embolism.
MedLine Citation:
PMID:  11182271     Owner:  NLM     Status:  MEDLINE    
In general, massive pulmonary embolism induces severe right ventricular overload, but pathological changes in the right ventricle due to pulmonary embolism is rarely seen. In this report, we describe two autopsy cases of massive pulmonary embolism without pre-existing cardiopulmonary disease. Both cases were accompanied by myocarditis-like changes in the right ventricle and infiltration of a number of polymorphonuclear neutrophils and mononuclear cells into the dilated right ventricular wall. Transmural or subendocardial coagulation necrosis was not apparent. Almost all of the mononuclear cells were immunohistochemically revealed to be CD68-positive macrophages. We speculated that these findings resulted from ischemia due to massive pulmonary embolism.
K Iwadate; K Tanno; M Doi; T Takatori; Y Ito
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Forensic science international     Volume:  116     ISSN:  0379-0738     ISO Abbreviation:  Forensic Sci. Int.     Publication Date:  2001 Feb 
Date Detail:
Created Date:  2001-02-22     Completed Date:  2001-04-26     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7902034     Medline TA:  Forensic Sci Int     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  189-95     Citation Subset:  IM    
Department of Legal Medicine, Faculty of Medicine, Tokyo Medical and Dental University, Yushima 1-5-45, Bunkyo-ku, 113-8519, Tokyo, Japan.
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MeSH Terms
Accidents, Traffic
Antigens, CD / analysis
Antigens, Differentiation, Myelomonocytic / analysis
Cause of Death*
Leg Injuries / complications
Leukocytes, Mononuclear / pathology
Myocardial Ischemia / etiology*,  pathology*
Myocarditis / etiology*,  pathology*
Neutrophils / pathology
Pulmonary Embolism / complications*
Ventricular Dysfunction, Right / etiology*,  pathology*
Reg. No./Substance:
0/Antigens, CD; 0/Antigens, Differentiation, Myelomonocytic; 0/CD68 antigen, human

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