Document Detail

Two cases of digital defects in Macaca mulatta infants and a survey of the literature.
MedLine Citation:
PMID:  12110053     Owner:  NLM     Status:  MEDLINE    
Although congenital digital defects, particularly polydactyly, have been reported frequently in humans, their occurrence in rhesus macaques is relatively rare. We observed two cases of spontaneous digital defects in male rhesus monkey infants recently born at the California Regional Primate Research Center. One infant exhibited bilateral postaxial polydactyly and the other infant had bilateral oligodactyly with unilateral phalangeal duplication. In this report, we present the clinical/pathological details of these cases as well as discuss the embryology of normal and abnormal limb development. We will also summarize a variety of spontaneous and experimentally induced digital defects that have been reported in several nonhuman primate species.
L Brignolo; R Tarara; P E Peterson; A G Hendrickx
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, U.S. Gov't, P.H.S.; Review    
Journal Detail:
Title:  Journal of medical primatology     Volume:  31     ISSN:  0047-2565     ISO Abbreviation:  J. Med. Primatol.     Publication Date:  2002 Apr 
Date Detail:
Created Date:  2002-07-11     Completed Date:  2002-07-30     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0320626     Medline TA:  J Med Primatol     Country:  Denmark    
Other Details:
Languages:  eng     Pagination:  98-103     Citation Subset:  IM    
California Regional Primate Research Center, University of California, Davis, CA95616-8542, USA.
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MeSH Terms
Animals, Newborn
Embryonic and Fetal Development
Fingers / abnormalities*,  embryology
Macaca mulatta*
Polydactyly / pathology,  veterinary*
Grant Support

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