Document Detail


Two cases of atypical membranous aplasia cutis with hair collar sign: one with dermal melanocytosis, and the other with naevus flammeus.
MedLine Citation:
PMID:  16045676     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We report two atypical cases of membranous aplasia cutis surrounded by a rim of hairs, one case associated with dense dermal melanocytosis and the other with naevus flammeus, with characteristic clinical features. A rim of hypertrichosis, 'hair collar' sign, is proposed to have a close association with neuroectodermal defects. A failure of the normal closure of the cranial neural tube might have affected foetal skin development, including melanoblast migration and capillary network formation. The changes in the present cases, as well as the hair collar sign may suggest a complex hamartomatous nature of membranous aplasia cutis.
Authors:
Y Fujita; K Yokota; M Akiyama; S Machino; D Inokuma; K Arita; C Kimura; H Shimizu
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Clinical and experimental dermatology     Volume:  30     ISSN:  0307-6938     ISO Abbreviation:  Clin. Exp. Dermatol.     Publication Date:  2005 Sep 
Date Detail:
Created Date:  2005-07-27     Completed Date:  2005-11-21     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7606847     Medline TA:  Clin Exp Dermatol     Country:  England    
Other Details:
Languages:  eng     Pagination:  497-9     Citation Subset:  IM    
Affiliation:
Department of Plastic Surgery, Hakodate Central General Hospital, Hakodate, Japan. yfuijita@med.hokudai.ac.jp
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MeSH Terms
Descriptor/Qualifier:
Ectodermal Dysplasia / pathology*
Female
Humans
Hypertrichosis / pathology*
Infant
Male
Melanosis / pathology*
Port-Wine Stain / pathology*
Scalp Dermatoses / pathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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