Document Detail

Two cases of acromegaly in a family.
MedLine Citation:
PMID:  9228457     Owner:  NLM     Status:  MEDLINE    
We report two cases of acromegaly due to pituitary adenoma without any other endocrinopathy in a family. The patients had high plasma GH and were improved by transsphenoidal adenomectomy. Acromegaly is usually a clinical syndrome of sporadic nonfamilial occurrence. The familial occurrence of acromegaly not associated with multiple endocrine neoplasia is very rare. Our patients are unlikely to be associated with the multiple endocrine neoplasia type 1 syndrome. Here we describe two patients with acromegaly, a father and his daughter, and review familial cases reported.
S Kakiya; A Kawakubo; K Toyama; M Yamamoto
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Endocrine journal     Volume:  44     ISSN:  0918-8959     ISO Abbreviation:  Endocr. J.     Publication Date:  1997 Apr 
Date Detail:
Created Date:  1997-08-18     Completed Date:  1997-08-18     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  9313485     Medline TA:  Endocr J     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  227-31     Citation Subset:  IM    
Department of Internal Medicine, Anjo Kosei Hospital, Aichi, Japan.
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MeSH Terms
Acromegaly / genetics*
Adenoma, Acidophil / genetics
Adenoma, Chromophobe / genetics
Magnetic Resonance Imaging
Middle Aged
Multiple Endocrine Neoplasia / genetics
Pituitary Neoplasms / genetics

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