| Two cases of Gamma Knife radiosurgery for low-grade optic chiasm glioma. | |
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MedLine Citation:
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PMID: 9032859 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The effect of radiosurgery on optic gliomas is uncertain. We report two cases of low-grade glioma of the optic nerve and chiasm treated by transcranial subtotal removal and Gamma Knife radiosurgery. The first case was a 2-year-old boy, admitted with visual disturbance and nystagmus. Histopathological examination showed a pilocytic astrocytoma. The tumor volume was 14.4 cm3. Dose planning was performed using axial and coronal T1-weighted enhanced images. The marginal dose was 12 Gy at the 40% isodose line. The dose to the optic apparatus was less than 9 Gy. The second case was a 47-year-old woman, admitted to our hospital with headache and visual disturbance. The histopathological findings showed a fibrillary astrocytoma. The tumor volume was 12.3 cm3. The marginal dose was 14.4 Gy at the 40% isodose curve. The follow-up periods for the two cases were 24 and 43 months, respectively. In both cases the most recent follow-up magnetic resonance scan showed a marked decrease in tumor size, and visual symptoms were improved. No postradiosurgical complications have developed to date. Gamma Knife radiosurgery could be an effective adjuvant therapy for low-grade optic glioma. However, long-term follow-up is required for further evaluation of the efficacy and potential side effects. |
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Authors:
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Y J Lim; W Leem |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Stereotactic and functional neurosurgery Volume: 66 Suppl 1 ISSN: 1011-6125 ISO Abbreviation: Stereotact Funct Neurosurg Publication Date: 1996 |
Date Detail:
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Created Date: 1997-05-28 Completed Date: 1997-05-28 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8902881 Medline TA: Stereotact Funct Neurosurg Country: SWITZERLAND |
Other Details:
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Languages: eng Pagination: 174-83 Citation Subset: IM |
Affiliation:
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Department of Neurosurgery, School of Medicine, Kyung Hee University, Seoul, Korea. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Child, Preschool Female Glioma / pathology, surgery* Humans Magnetic Resonance Imaging Male Middle Aged Optic Chiasm / pathology, surgery* Optic Nerve Diseases / pathology, surgery* Radiation Dosage |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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