Document Detail

Two cases of Gamma Knife radiosurgery for low-grade optic chiasm glioma.
MedLine Citation:
PMID:  9032859     Owner:  NLM     Status:  MEDLINE    
The effect of radiosurgery on optic gliomas is uncertain. We report two cases of low-grade glioma of the optic nerve and chiasm treated by transcranial subtotal removal and Gamma Knife radiosurgery. The first case was a 2-year-old boy, admitted with visual disturbance and nystagmus. Histopathological examination showed a pilocytic astrocytoma. The tumor volume was 14.4 cm3. Dose planning was performed using axial and coronal T1-weighted enhanced images. The marginal dose was 12 Gy at the 40% isodose line. The dose to the optic apparatus was less than 9 Gy. The second case was a 47-year-old woman, admitted to our hospital with headache and visual disturbance. The histopathological findings showed a fibrillary astrocytoma. The tumor volume was 12.3 cm3. The marginal dose was 14.4 Gy at the 40% isodose curve. The follow-up periods for the two cases were 24 and 43 months, respectively. In both cases the most recent follow-up magnetic resonance scan showed a marked decrease in tumor size, and visual symptoms were improved. No postradiosurgical complications have developed to date. Gamma Knife radiosurgery could be an effective adjuvant therapy for low-grade optic glioma. However, long-term follow-up is required for further evaluation of the efficacy and potential side effects.
Y J Lim; W Leem
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Stereotactic and functional neurosurgery     Volume:  66 Suppl 1     ISSN:  1011-6125     ISO Abbreviation:  Stereotact Funct Neurosurg     Publication Date:  1996  
Date Detail:
Created Date:  1997-05-28     Completed Date:  1997-05-28     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8902881     Medline TA:  Stereotact Funct Neurosurg     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  174-83     Citation Subset:  IM    
Department of Neurosurgery, School of Medicine, Kyung Hee University, Seoul, Korea.
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MeSH Terms
Child, Preschool
Glioma / pathology,  surgery*
Magnetic Resonance Imaging
Middle Aged
Optic Chiasm / pathology,  surgery*
Optic Nerve Diseases / pathology,  surgery*
Radiation Dosage

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