| Two brothers with a symptomatic thoracic disc herniation at T11-T12: clinical report. | |
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MedLine Citation:
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PMID: 19266152 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: In contrast to what is commonly believed, thoracic disc herniations are not rare lesions. Their etiopathogenesis is largely unknown, but may be linked to trauma, Scheuermann's disease or a degenerative back. OBJECTIVE: We report two brothers with a symptomatic thoracic disc herniation at T11-T12 and address the possibility of a genetic factor as well as other factors in the etiopathogenesis of (symptomatic) thoracic disc herniations. CLINICAL FEATURES: Both brothers were in their early thirties and had a physically demanding job, however, only the first one was a smoker and was diagnosed with Scheuermann's disease. CONCLUSION: The etiology of thoracic disc herniations is likely multifactorial. Their occurrence in siblings may reflect some genetic predisposition or may be merely coincidental, given the high prevalence of thoracic disc herniations in asymptomatic individuals. Further research, including genetic studies, is warranted. |
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Authors:
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Geke M Overvliet; Emile A M Beuls; Mariel Ter Laak-Poort; Erwin M J Cornips |
Publication Detail:
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Type: Case Reports; Journal Article Date: 2009-03-06 |
Journal Detail:
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Title: Acta neurochirurgica Volume: 151 ISSN: 0942-0940 ISO Abbreviation: Acta Neurochir (Wien) Publication Date: 2009 Apr |
Date Detail:
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Created Date: 2009-04-24 Completed Date: 2009-06-26 Revised Date: 2009-11-11 |
Medline Journal Info:
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Nlm Unique ID: 0151000 Medline TA: Acta Neurochir (Wien) Country: Austria |
Other Details:
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Languages: eng Pagination: 393-6 Citation Subset: IM |
Affiliation:
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Department of Neurosurgery, Maastricht University Medical Center, AZ, Maastricht, The Netherlands. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Back Pain / etiology Comorbidity Diskectomy, Percutaneous Genetic Predisposition to Disease Humans Intervertebral Disk Displacement / etiology*, pathology* Magnetic Resonance Imaging Male Occupational Diseases / epidemiology Paraparesis / etiology, pathology, surgery Risk Factors Scheuermann Disease / epidemiology Siblings Smoking / epidemiology Spinal Cord / pathology, physiopathology Spinal Cord Compression / etiology*, pathology*, surgery Thoracic Vertebrae / pathology*, radiography, surgery Thoracoscopy Treatment Outcome |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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