| Two Rabs for exosome release. | |
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MedLine Citation:
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PMID: 20027197 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Exosomes are endosome-derived membrane vesicles that are key for intercellular communication in the immune system and elsewhere. Rab27A and Rab27B GTPases and two of their cognate effector proteins seem to be needed to drive the physiologically important exosome-release process in certain cell types. |
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Authors:
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Suzanne R Pfeffer |
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Publication Detail:
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Type: News |
Journal Detail:
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Title: Nature cell biology Volume: 12 ISSN: 1476-4679 ISO Abbreviation: Nat. Cell Biol. Publication Date: 2010 Jan |
Date Detail:
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Created Date: 2009-12-22 Completed Date: 2010-01-12 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100890575 Medline TA: Nat Cell Biol Country: England |
Other Details:
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Languages: eng Pagination: 3-4 Citation Subset: IM |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Cell Communication Endosomes Exosomes / physiology* Humans rab GTP-Binding Proteins / metabolism* |
| Chemical | |
Reg. No./Substance:
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EC 3.6.1.-/rab GTP-Binding Proteins; EC 3.6.1.-./RAB27A protein, human; EC 3.6.1.-./Rab27B protein, human |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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