Document Detail


Two-Dimensional Visualization of Multicolor FISH-Generated Data as a Helpful Tool for the Analysis and Understanding of Cytogenetic and Chromosomal Alterations in Melanocytic Lesions.
MedLine Citation:
PMID:  23542716     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
: For the evaluation of data generated by multicolor fluorescence in situ hybridization (FISH), we present here a synergistic approach that integrates the 3 most commonly used numerical algorithms in conjunction with 2 newly devised graphic tools for data visualization, namely "signal curves" and "rhombic heat maps." These two graphic tools provide information additional to the currently used numerical algorithms and thus facilitate the recognition and compensation of inherent errors that occur with the numerical method.
Authors:
Katrin Kerl; Schärer Leo; Raphael Hesse; Benedikt Hesse; Palmedo Gabriela; Luis Requena; Thomas Wiesner; Heinz Kutzner
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The American Journal of dermatopathology     Volume:  35     ISSN:  1533-0311     ISO Abbreviation:  Am J Dermatopathol     Publication Date:  2013 Apr 
Date Detail:
Created Date:  2013-04-01     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7911005     Medline TA:  Am J Dermatopathol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  151-8     Citation Subset:  IM    
Affiliation:
*Department of Dermatology, Zürich University Hospital, Zürich, Switzerland †Dermatopathologie Friedrichshafen, Friedrichshafen, Germany ‡Department of Dermatology, Fundación Jiménez Díaz, Universidad Autónoma, Madrid, Spain §Medical University of Graz, Austria.
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