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Two Different Days of Transcranial Doppler Examinations Should Be Performed for Detection of Right-to-Left Shunt in Acute Stroke Patients.
MedLine Citation:
PMID:  22188538     Owner:  NLM     Status:  Publisher    
BACKGROUND: We investigated how many contrast-transcranial Doppler (c-TCD) examinations should be performed on different days in patients with acute stroke. METHODS: Consecutive acute stroke patients within 24 hours of onset were enrolled. Presence of RLS was examined using c-TCD examinations on days 1, 7, and 14. Each c-TCD examination used one test without Valsalva maneuver (VM) and three tests with VM. Patients were diagnosed with RLS when TCD detected ≥1 microembolic signal on ≥1 c-TCD examination on any of the days 1, 7, or 14. RESULTS: One hundred seventy patients (105 men [62%]; median age, 74 [IQR, 66-81] years) were enrolled. RLS was diagnosed in 45 patients (26%). RLS was identified on day 1 in 30 patients (18%), on day 7 in 28 patients (16%), and on day 14 in 23 patients (14%; P= .143). Detection rate of RLS by combining day 1 and 7 examinations was significantly higher than that of day 1 alone (25% vs 18%, P < .001). However, the rate did not increase when results of day 14 were added (25% vs 26%, P= .250). CONCLUSIONS: c-TCD examinations should be performed on at least two different days to assess the prevalence of RLS. J Neuroimaging 2011;XX:1-5.
Junya Aoki; Kazumi Kimura; Yasuyuki Iguchi; Kenichiro Sakai; Yuki Sakamoto; Yuka Terasawa; Kensaku Shibazaki; Kazuto Kobayashi
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-12-20
Journal Detail:
Title:  Journal of neuroimaging : official journal of the American Society of Neuroimaging     Volume:  -     ISSN:  1552-6569     ISO Abbreviation:  -     Publication Date:  2011 Dec 
Date Detail:
Created Date:  2011-12-22     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9102705     Medline TA:  J Neuroimaging     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2011 by the American Society of Neuroimaging.
From the Department of Stroke Medicine, Kawasaki Medical School, Kurashiki-City, Okayama, Japan.
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