Document Detail


Twinning in humans: maternal heterogeneity in reproduction and survival.
MedLine Citation:
PMID:  21561975     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
While humans usually give birth to singletons, dizygotic twinning occurs at low rates in all populations worldwide. We evaluate two hypotheses that have differing expectations about the effects of bearing twins on maternal lifetime reproduction and survival. The maternal depletion hypothesis argues that mothers of twins will suffer negative outcomes owing to the higher physiological costs associated with bearing multiples. Alternatively, twinning, while costly, may indicate mothers with a greater capacity to bear that cost. Drawing from the vast natural fertility data in the Utah Population Database, we compared the reproductive and survival events of 4603 mothers who bore twins and 54 183 who had not. These mothers were born between 1807 and 1899, lived at least to the age of 50 years and married once to men who were alive when their wives were 50. Results from proportional hazards and regression analyses are consistent with the second hypothesis. Mothers of twins exhibit lower postmenopausal mortality, shorter average inter-birth intervals, later ages at last birth and higher lifetime fertility than their singleton-only bearing counterparts. From the largest historical sample of twinning mothers yet published, we conclude that bearing twins is more likely for those with a robust phenotype and is a useful index of maternal heterogeneity.
Authors:
Shannen L Robson; Ken R Smith
Related Documents :
8251205 - Today or in the past? the origins of ischaemic heart disease.
8388785 - Effects of bases and additives on release of carbon dioxide from effervescent supposito...
15945665 - Rate constants and branching ratios for the dissociative recombination of c3d(+)7 and c...
19886585 - Setting a goal to reduce teen births in milwaukee by 2015.
21253315 - What is the 'objective' differential factor of diarrhea in infancy?: normal state versu...
4088795 - Shape constancy and slant perception at birth.
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't     Date:  2011-05-11
Journal Detail:
Title:  Proceedings. Biological sciences / The Royal Society     Volume:  278     ISSN:  1471-2954     ISO Abbreviation:  Proc. Biol. Sci.     Publication Date:  2011 Dec 
Date Detail:
Created Date:  2011-11-14     Completed Date:  2012-06-04     Revised Date:  2013-06-30    
Medline Journal Info:
Nlm Unique ID:  101245157     Medline TA:  Proc Biol Sci     Country:  England    
Other Details:
Languages:  eng     Pagination:  3755-61     Citation Subset:  IM    
Affiliation:
Department of Anthropology, University of Utah, Salt Lake City, UT, USA. robson@umnh.utah.edu
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Birth Intervals
Female
Fertility
Humans
Linear Models
Maternal Age
Mortality
Parity
Phenotype
Postmenopause
Pregnancy
Pregnancy, Multiple / physiology*,  statistics & numerical data
Utah
Grant Support
ID/Acronym/Agency:
AG022095/AG/NIA NIH HHS
Comments/Corrections
Comment In:
Proc Biol Sci. 2012 Jul 7;279(1738):2510-1; discussion 2512-4   [PMID:  22496189 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Within-host parasite cooperation and the evolution of virulence.
Next Document:  Can insect egg deposition 'warn' a plant of future feeding damage by herbivorous larvae?