Document Detail


Twinning and conjoined placentation in mice.
MedLine Citation:
PMID:  7097179     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Spontaneous and experimentally induced twinning and conjoined placentation were studied in Swiss-Webster (SW) mice. Conjoined placentation was noticed at a rate of 0.4% for twins and 0.06% for triplets. Placentally conjoined embryos were either symmetrical or asymmetrical. A single spontaneous monozygotic conjoined twin was observed among 2,000 blastocysts cultured in vitro. The yield of twins could not be increased by manipulating explanted embryos in vitro, or by treating in utero during the early postimplantation stage of development with vincristine.
Authors:
Y J Wan; T C Wu; I Damjanov
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of experimental zoology     Volume:  221     ISSN:  0022-104X     ISO Abbreviation:  J. Exp. Zool.     Publication Date:  1982 May 
Date Detail:
Created Date:  1982-09-10     Completed Date:  1982-09-10     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0375365     Medline TA:  J Exp Zool     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  81-6     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Embryo, Mammalian / drug effects
Embryonic Development
Female
Litter Size*
Mice
Placenta / pathology*
Pregnancy
Twins, Conjoined / pathology*
Vincristine / pharmacology
Chemical
Reg. No./Substance:
57-22-7/Vincristine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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