| Twin trisomies-Edward and Patau syndromes. | |
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MedLine Citation:
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PMID: 18440001 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To report the rare occurrence of dichorionic diamniotic twins with dissimilar aneuploidies. DESIGN: Case report. SETTING: District general hospital. PATIENT(S): A 36-year-old woman conceived by in vitro fertilization. Dichorionic diamniotic twins were found to have elevated nuchal translucencies and cystic hygromas. Intrauterine deaths occurred at 13 and 17 weeks gestation. INTERVENTION(S): Medical termination of pregnancy. MAIN OUTCOME MEASURE(S): Karyotypes. RESULT(S): Cytogenetic studies confirmed Edward's and Patau's syndromes. CONCLUSION(S): The aetiology is unknown but maternal age and in vitro fertilization may be linked since the incidence of aneuploidy rises with maternal age and the incidence of twins' increases with assisted reproductive techniques. This case highlights the need for obstetricians to have good communication and counselling skills. |
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Authors:
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Nadine Massiah; Emma Griffiths; Vincent Bamigboye |
Publication Detail:
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Type: Case Reports; Journal Article Date: 2008-04-25 |
Journal Detail:
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Title: Fertility and sterility Volume: 90 ISSN: 1556-5653 ISO Abbreviation: Fertil. Steril. Publication Date: 2008 Nov |
Date Detail:
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Created Date: 2008-11-10 Completed Date: 2008-12-10 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0372772 Medline TA: Fertil Steril Country: United States |
Other Details:
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Languages: eng Pagination: 2011.e23-4 Citation Subset: IM |
Affiliation:
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Department of Obstetrics and Gynaecology, Furness General Hospital, Barrow in Furness, United Kingdom. nsmassiah@doctors.org.uk |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Abnormalities, Multiple
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genetics*,
pathology Abortion, Therapeutic Adult Age Factors Female Fertilization in Vitro / adverse effects* Fetal Death / genetics*, pathology Gestational Age Humans Karyotyping Lymphangioma, Cystic / genetics, pathology Nuchal Translucency Measurement Pregnancy Pregnancy, Multiple* Syndrome Trisomy* Twins / genetics* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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