Document Detail

Twin preterm neonates with cardiac toxicity related to lopinavir/ritonavir therapy.
MedLine Citation:
PMID:  19820426     Owner:  NLM     Status:  In-Process    
We report twin neonates who were born prematurely at 32 weeks of gestation to a mother with human immunodeficiency virus infection. One of the twins developed complete heart block and dilated cardiomyopathy related to lopinavir/ritonavir therapy, a boosted protease-inhibitor agent, while the other twin developed mild bradycardia. We recommend caution in the use of lopinavir/ritonavir in the immediate neonatal period.
Monica A McArthur; Stella U Kalu; Arlen R Foulks; Ashraf M Aly; Sunil K Jain; Janak A Patel
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Pediatric infectious disease journal     Volume:  28     ISSN:  1532-0987     ISO Abbreviation:  Pediatr. Infect. Dis. J.     Publication Date:  2009 Dec 
Date Detail:
Created Date:  2009-11-25     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8701858     Medline TA:  Pediatr Infect Dis J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1127-9     Citation Subset:  IM    
Department of Pediatrics, The University of Texas Medical Branch, Galveston, TX 77555-0371, USA.
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