| Twin pregnancy experimental model for transvaginal ultrasound-guided twin reduction in mares. | |
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MedLine Citation:
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PMID: 19183731 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Multiple pregnancies are still an important cause of noninfectious abortion, stillbirth, neonatal mortality, and significant delays in reproductive performance in mares. Despite new management techniques, reduction in multiple pregnancies is an ongoing preoccupation and challenge for the equine veterinarian. The aim of the present study was to establish a twin pregnancy experimental model in the mare to study the effectiveness of a transvaginal ultrasound-guided embryonic vesicle injection. Mares in heat were inseminated and then received an embryo at day 7 of the estrous cycle. At days 14 and 30, 53.5% (n = 23) and 23% (n = 10) of the mares, respectively, were carrying twins. Twin pregnancies were reduced at day 30 by transvaginal ultrasound-guided puncture of the embryonic vesicle (control, n = 5) or by transvaginal ultrasound-guided injection (TVUEVI) of 25 mg of amikacin into the embryonic vesicle (n = 5). The TVUEVI treatment had a 40% success rate and no significant variations in progesterone and prostaglandin metabolite were observed. Even though the technique does not seem very effective, the experimental model could be useful for clinical research in embryo reduction and early embryonic loss. |
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Authors:
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Ignacio Raggio; Réjean C Lefebvre; Pierre Poitras; Denis Vaillancourt; Alan K Goff |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Canadian veterinary journal. La revue vétérinaire canadienne Volume: 49 ISSN: 0008-5286 ISO Abbreviation: Can. Vet. J. Publication Date: 2008 Nov |
Date Detail:
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Created Date: 2009-02-02 Completed Date: 2009-04-27 Revised Date: 2009-11-18 |
Medline Journal Info:
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Nlm Unique ID: 0004653 Medline TA: Can Vet J Country: Canada |
Other Details:
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Languages: eng Pagination: 1093-8 Citation Subset: IM |
Affiliation:
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Department of Clinical Sciences, Faculté de médecine vétérinaire, Université de Montréal, 3200 rue Sicotte, Saint-Hyacinthe, Québec. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Amikacin
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therapeutic use Animals Female Gestational Age Horses Pregnancy Pregnancy Reduction, Multifetal / adverse effects, methods, veterinary* Pregnancy, Animal* Pregnancy, Multiple* Treatment Outcome Twins Ultrasonography, Prenatal / methods, veterinary* |
| Chemical | |
Reg. No./Substance:
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37517-28-5/Amikacin |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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