| Twin anemia polycythemia sequence from a prenatal perspective. | |
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MedLine Citation:
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PMID: 20373492 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVES: To describe the prevalence, management and outcome of spontaneous twin anemia polycythemia sequence (TAPS) diagnosed in the prenatal period. METHOD: Retrospective analysis of 142 consecutive monochorionic twin pregnancies not diagnosed with twin to twin transfusion syndrome. TAPS cases were identified based on the presence of discordant middle cerebral artery peak systolic velocity (MCA-PSV) measurements and signs suggestive of a chronic intertwin transfusion imbalance: either an elevated reticulocyte count in the anemic twin or the presence of few small unidirectional anastomoses during fetoscopy or at postnatal placental examination. RESULTS: Three cases were identified, giving an estimated prevalence of 2%. Prenatal interventions were tailored to the characteristics of each case and consisted of intrauterine transfusion and interruption of the shared circulation by cord coagulation or laser separation. CONCLUSION: In monochorionic twin pregnancies, TAPS is an uncommon prenatal finding. Nonetheless, its incidence seems high enough to recommend screening for this disease by MCA-PSV measurements. |
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Authors:
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Léonardo Gucciardo; Liesbeth Lewi; Pascal Vaast; Marzena Debska; Luc De Catte; Tim Van Mieghem; Elisa Done; Roland Devlieger; Jan Deprest |
Publication Detail:
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Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Prenatal diagnosis Volume: 30 ISSN: 1097-0223 ISO Abbreviation: Prenat. Diagn. Publication Date: 2010 May |
Date Detail:
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Created Date: 2010-05-04 Completed Date: 2010-09-13 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8106540 Medline TA: Prenat Diagn Country: England |
Other Details:
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Languages: eng Pagination: 438-42 Citation Subset: IM |
Affiliation:
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Department of Obstetrics and Gynecology, University Hospitals, Leuven, Belgium. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Anemia, Neonatal / epidemiology, surgery, ultrasonography* Arteriovenous Anastomosis / surgery, ultrasonography Belgium / epidemiology Blood Transfusion, Intrauterine Diseases in Twins / epidemiology, surgery, ultrasonography* Female Humans Infant, Newborn Laser Coagulation Middle Cerebral Artery / ultrasonography* Oligohydramnios / ultrasonography Placenta Diseases / ultrasonography* Polycythemia / epidemiology, surgery, ultrasonography* Pregnancy Prevalence Rheology Syndrome Ultrasonography, Prenatal* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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