Document Detail


The Twin Interdisciplinary Neuroticism Study.
MedLine Citation:
PMID:  23186546     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
The Twin Interdisciplinary Neuroticism Study (TWINS) is a three-wave study including >800 twin pairs from the northern part of the Netherlands. The aim of the study is to unravel why neuroticism reflects vulnerability to mental disorders. In this study, we focus on possible mechanisms underlying this vulnerability and their genetic and environmental origins. In total, 125 female twin pairs visited our psychophysiological laboratory. From these twin pairs DNA was isolated and both candidate gene and genome-wide genotyping were conducted. Future work includes studies of candidate genes. The study also participates in several meta-genome-wide association study (GWAS) consortia.
Authors:
Harriëtte Riese; Frühling V Rijsdijk; Harold Snieder; Johan Ormel
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-11-28
Journal Detail:
Title:  Twin research and human genetics : the official journal of the International Society for Twin Studies     Volume:  -     ISSN:  1832-4274     ISO Abbreviation:  Twin Res Hum Genet     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-11-28     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101244624     Medline TA:  Twin Res Hum Genet     Country:  -    
Other Details:
Languages:  ENG     Pagination:  1-3     Citation Subset:  -    
Affiliation:
Interdisciplinary Center Pathology of Emotion regulation (ICPE), Department of Psychiatry, Graduate School of Behavioral and Cognitive Neurosciences (BCN), Graduate School of Health Sciences (SHARE), University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
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