Document Detail


Twenty-four-hour quantitative thallium imaging for predicting beneficial revascularization.
MedLine Citation:
PMID:  7859773     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
To determine the utility of 24-h thallium single-photon emission tomographic imaging for the assessment of myocardial viability, 40 patients with persistently decreased uptake on 3-h delayed imaging after exercise were studied before and after bypass surgery (n = 34) or coronary angioplasty (n = 6). Wall motion improvement after revascularization was also analysed in 23 patients with respect to the segments with and without 24-h redistribution. Of a total of 113 segments without redistribution at 3-h imaging after exercise, 62 (55%) demonstrated redistribution at 24 h. After revascularization 57 (92%) of these 62 segments revealed improvement of thallium uptake. On the other hand 40 (78%) of the 51 segments with persistently decreased thallium uptake until 24 h did not show improvement of uptake after revascularization. Of the 15 segments with > 50% relative thallium uptake and without redistribution on 24-h images, ten showed improvement of thallium uptake after revascularization. Hence higher uptake even without 24-h redistribution may indicate viability. Regional wall motion improved in 22 of 23 segments with redistribution on 24-h images, and did not improve after revascularization in 19 of 22 segments without redistribution at 24 h. These data suggest that 24-h late imaging with quantitative analysis may provide reliable information about reversible myocardial ischaemia in segments that demonstrate a fixed perfusion abnormality on conventional 3-h delayed imaging.
Authors:
J Taki; K Nakajima; H Bunko; M Kawasuji; N Tonami; K Hisada
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European journal of nuclear medicine     Volume:  21     ISSN:  0340-6997     ISO Abbreviation:  Eur J Nucl Med     Publication Date:  1994 Nov 
Date Detail:
Created Date:  1995-03-21     Completed Date:  1995-03-21     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7606882     Medline TA:  Eur J Nucl Med     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  1212-7     Citation Subset:  IM    
Affiliation:
Department of Nuclear Medicine, Kanazawa University School of Medicine, Japan.
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MeSH Terms
Descriptor/Qualifier:
Angioplasty, Transluminal, Percutaneous Coronary*
Coronary Artery Bypass*
Exercise Test
Female
Gated Blood-Pool Imaging
Heart / radionuclide imaging*
Humans
Image Processing, Computer-Assisted
Male
Middle Aged
Myocardial Contraction / physiology
Myocardial Ischemia / radionuclide imaging*,  therapy
Predictive Value of Tests
Thallium Radioisotopes / diagnostic use*
Time Factors
Tomography, Emission-Computed, Single-Photon*
Chemical
Reg. No./Substance:
0/Thallium Radioisotopes

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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