| Twenty-four-hour ocular perfusion pressure in primary open-angle glaucoma. | |
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MedLine Citation:
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PMID: 20516145 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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AIM: To compare the 24 h intraocular pressure (IOP), blood pressure (BP), and perfusion pressure (PP) of primary open-angle glaucoma (POAG) patients and healthy individuals. METHODS: 24 healthy individuals and 29 POAG patients underwent IOP and BP measurements every 2 h, starting at 08:00 until 06:00 of the next morning. IOP measurements were made by a masked observer with a Goldmann tonometer at the slit-lamp from 08:00 to 22:00 and with the Perkins tonometer in supine position from 24:00 to 06:00. Systolic and diastolic BP (SBP and DBP) measurements were performed with an automated device. RESULTS: Mean IOPs in POAG patients were significantly higher at all time intervals (p<0.001). The mean SBP was significantly higher in POAG patients from 04:00 to 10:00, and also at 14:00 and 18:00 (p<0.05). In POAG patients, the mean DBP was significantly higher at 08:00 and 10:00, but was significantly lower at 04:00 (p<0.05). In POAG patients, the mean systolic perfusion pressure (SPP) was significantly higher at 08:00 and 10:00 (p<0.01), whereas the mean diastolic perfusion pressure (DPP) was significantly lower from 24:00 to 06:00 (p<0.05). CONCLUSION: Although higher SPPs are observed in POAG patients during the morning, lower DPPs are found during the night. |
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Authors:
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Vital P Costa; Jesus Jimenez-Roman; Felix Gil Carrasco; Alvaro Lupinacci; Alon Harris |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2010-06-01 |
Journal Detail:
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Title: The British journal of ophthalmology Volume: 94 ISSN: 1468-2079 ISO Abbreviation: Br J Ophthalmol Publication Date: 2010 Oct |
Date Detail:
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Created Date: 2010-10-07 Completed Date: 2010-12-06 Revised Date: 2011-09-06 |
Medline Journal Info:
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Nlm Unique ID: 0421041 Medline TA: Br J Ophthalmol Country: England |
Other Details:
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Languages: eng Pagination: 1291-4 Citation Subset: IM |
Affiliation:
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Department of Ophthalmology, University of Campinas, Campinas, Rua Bahia 1087, São Paulo, Brazil. vp.costa@uol.com.br |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Blood Pressure / physiology* Case-Control Studies Circadian Rhythm Eye / blood supply* Female Glaucoma, Open-Angle / physiopathology* Humans Intraocular Pressure / physiology* Male Middle Aged Prospective Studies |
| Comments/Corrections | |
Comment In:
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Br J Ophthalmol. 2011 Aug;95(8):1175-6
[PMID:
21617157
]
Br J Ophthalmol. 2010 Oct;94(10):1273-4 [PMID: 20813741 ] |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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