| Twenty-four-hour measurement of IOP in rabbits using rebound tonometer. | |
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MedLine Citation:
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PMID: 23279703 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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PURPOSE: To observe the Intraocular pressure (IOP) measurements over a 24-h period in New Zealand white rabbits. METHODS: Thirty-four normal New Zealand white rabbits (68 eyes) were included in this study. The IOP values were determined with a rebound tonometer (RBT, Icare VET). Measurements were always obtained in the right eye first. RESULTS: The data showed that there was no significant difference in IOP between measurements, which indicated that the RBT showed good repeatability in this study (P = 0.920). There was no statistically significant difference between genders (P = 0.943). The IOP in right eyes was a little higher than left eyes (F = 45.96, P < 0.001). Comparison of the true IOP and RBT results over the entire pressure range (8-100 mmHg) revealed a statistically significant difference between them (P < 0.001). The mean difference between the RBT and true IOP (RBT-True IOP) was -22.65 ± 9.52 mmHg with 95% confidence interval (-27.1, -18.2 mmHg). In the light period (7 AM to 7 PM), the IOP was a little lower than during the dark period (8 PM to 6 AM); 9 AM and 2 PM were the lowest measurements (10 mmHg, 9.625 mmHg), and 10 AM (14.125 mmHg)was the highest measurement during the 24-h period. CONCLUSIONS: The IOP obtained by RBT underestimated the true IOP but the RBT had a good repeatability in IOP measurements. In the light period (7 AM to 7 PM), the IOP was a little lower than during the dark period (8 PM to 6 AM), which may be beneficial to the intervention therapy observation of glaucoma research in rabbits. |
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Authors:
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Xiaogang Wang; Jing Dong; Qiang Wu |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2013-1-1 |
Journal Detail:
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Title: Veterinary ophthalmology Volume: - ISSN: 1463-5224 ISO Abbreviation: Vet Ophthalmol Publication Date: 2013 Jan |
Date Detail:
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Created Date: 2013-1-2 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100887377 Medline TA: Vet Ophthalmol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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© 2012 American College of Veterinary Ophthalmologists. |
Affiliation:
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Department of Ophthalmology, Affiliated Sixth People's Hospital Shanghai Jiao Tong University, Shanghai, China. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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