| Twenty-four-hour ambulatory esophageal pH monitoring in the diagnosis of acid reflux-related chronic cough. | |
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MedLine Citation:
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PMID: 9076302 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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To define the role of ambulatory pH monitoring in evaluating chronic cough, we studied esophageal pH values of patients referred to a gastroenterology laboratory. Chronic cough was evaluated in 31 patients, who were grouped based on response to treatments; 11 patients (35.5%) had gastroesophageal reflux (GER)-related cough, 11 (35.5%) had pulmonary/otorhinolaryngologic-related cough (1 bronchitis, 6 asthma, 2 postnasal drip, 1 pneumonia), and 9 patients (29%) had cough of unknown etiology. Esophageal pH values of groups were compared. Excessive acid reflux distally (upright and supine) and proximally (upright) and cough symptom frequency related to acid reflux were significantly higher in patients with GER. Esophageal pH monitoring had good sensitivity (91%), specificity (82%), and positive (83%) and negative (90%) predictive values in identifying GER-related cough. In summary, ambulatory pH monitoring is an excellent test for identifying patients with GER-related cough. |
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Authors:
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M F Vaezi; J E Richter |
Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Southern medical journal Volume: 90 ISSN: 0038-4348 ISO Abbreviation: South. Med. J. Publication Date: 1997 Mar |
Date Detail:
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Created Date: 1997-04-17 Completed Date: 1997-04-17 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0404522 Medline TA: South Med J Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 305-11 Citation Subset: AIM; IM |
Affiliation:
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Division of Gastroenterology, University of Alabama at Birmingham, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Analysis of Variance Asthma / diagnosis Bronchitis / diagnosis Chronic Disease Cough / etiology*, physiopathology Esophagogastric Junction / physiopathology Esophagus / physiopathology* Female Gastric Acid Gastric Acidity Determination Gastroesophageal Reflux / complications, diagnosis*, physiopathology Humans Hydrogen-Ion Concentration Male Manometry Middle Aged Monitoring, Ambulatory* Nose Diseases / diagnosis Pneumonia / diagnosis Posture Predictive Value of Tests Pressure Sensitivity and Specificity Supine Position |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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