Document Detail

Twenty-four-hour ambulatory blood pressure pattern in youngsters with a different family history of hypertension: the Dutch Hypertension and Offspring Study.
MedLine Citation:
PMID:  2632748     Owner:  NLM     Status:  MEDLINE    
The offspring of hypertensive parents in general show higher casual blood pressure levels during adolescence than the offspring of normotensive parents. Comparative ambulatory blood pressure measurements might reveal the stability and pattern of this difference during circadian blood pressure variation. We studied the 24-h ambulatory blood pressure (Space-Labs 90202 monitor, Redmond, Washington, USA) in youngsters with two hypertensive parents (high; n = 62), with one hypertensive parent (mixed; n = 51) and with no hypertensive parent (low; n = 42). The pattern for both systolic and diastolic blood pressure in the three groups ran parallel, with the high group continuously at a higher level. A clear difference in systolic blood pressure was observed during the day period (high minus low: 5.4 mmHg; 95% confidence range 2.5-8.3). Our data show that offspring of hypertensive parents differ in ambulatory blood pressure levels, but not in the circadian pattern, from the offspring of normotensive parents.
I M van Hooft; D E Grobbee; H J Waal-Manning; A Hofman
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of hypertension. Supplement : official journal of the International Society of Hypertension     Volume:  7     ISSN:  0952-1178     ISO Abbreviation:  J Hypertens Suppl     Publication Date:  1989 Dec 
Date Detail:
Created Date:  1990-05-11     Completed Date:  1990-05-11     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8501422     Medline TA:  J Hypertens Suppl     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  S66-7     Citation Subset:  IM    
Department of Epidemiology, Erasmus University Medical School, Rotterdam, The Netherlands.
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MeSH Terms
Blood Pressure / physiology*
Blood Pressure Monitors
Circadian Rhythm / physiology*
Hypertension / genetics,  physiopathology*
Reference Values

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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