Document Detail


Twelve-month results of nonsurgical radiofrequency energy micro-remodeling for stress incontinence.
MedLine Citation:
PMID:  15378235     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This pilot clinical trial was performed to evaluate the safety and impact on quality of life and incontinence episode frequency of nonsurgical radiofrequency energy (RF) tissue micro-remodeling in women with stress urinary incontinence (SUI). The palpation-guided treatment produces focal denaturation of submucosal collagen, resulting in reduced luminal wall compliance without luminal narrowing. Forty-one women suffering from SUI associated with urethral hypermobility were enrolled into four treatment groups which differed in total number and lower urinary tract location of micro-remodeling sites. No serious and only limited minor adverse events were associated with the treatment. Incidence of quality of life score improvement at 12 months ranged from 75 to 78%, and statistically significant incontinence episode frequency reduction was demonstrated by three of four treatment groups. RF micro-remodeling demonstrated 12-month safety, quality of life improvement, and incontinence episode frequency reduction. No one treatment group demonstrated clear superiority in efficacy outcomes.
Authors:
Mariano Sotomayor; Guillermo Feria Bernal
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Publication Detail:
Type:  Clinical Trial; Controlled Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't     Date:  2004-09-17
Journal Detail:
Title:  International urogynecology journal and pelvic floor dysfunction     Volume:  16     ISSN:  -     ISO Abbreviation:  Int Urogynecol J Pelvic Floor Dysfunct     Publication Date:    2005 May-Jun
Date Detail:
Created Date:  2005-05-05     Completed Date:  2005-08-30     Revised Date:  2011-08-18    
Medline Journal Info:
Nlm Unique ID:  9514583     Medline TA:  Int Urogynecol J Pelvic Floor Dysfunct     Country:  England    
Other Details:
Languages:  eng     Pagination:  192-6; discussion 196     Citation Subset:  IM    
Affiliation:
Department of Urology, Salvador Zubirán National Nutrition Institute, Mexico City, Mexico. pedelstein@novasysmedical.com
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Aged, 80 and over
Collagen
Female
Humans
Middle Aged
Patient Satisfaction
Quality of Life
Radio Waves / therapeutic use*
Temperature
Treatment Outcome
Urinary Incontinence, Stress / therapy*
Chemical
Reg. No./Substance:
9007-34-5/Collagen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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