Document Detail

Turning ON the switch--RhoGEFs in plants.
MedLine Citation:
PMID:  16406756     Owner:  NLM     Status:  MEDLINE    
Plant ROPs (or RACs) are Ras-related, small GTP-binding proteins that function as molecular switches in numerous signaling cascades. ROPs (RACs) cycle between a GDP-bound, inactive state and a GTP-bound, active state. Activation requires guanine-nucleotide exchange factors (GEFs), which were not identified in plants until recently. Alfred Wittinghofer and co-workers' description of a group of plant-specific RhoGEFs opens the way for the elucidation of ROP signaling cascades from membrane receptors to responses.
Keren Shichrur; Shaul Yalovsky
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2006-01-06
Journal Detail:
Title:  Trends in plant science     Volume:  11     ISSN:  1360-1385     ISO Abbreviation:  Trends Plant Sci.     Publication Date:  2006 Feb 
Date Detail:
Created Date:  2006-02-20     Completed Date:  2006-06-23     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  9890299     Medline TA:  Trends Plant Sci     Country:  England    
Other Details:
Languages:  eng     Pagination:  57-9     Citation Subset:  IM    
Department of Plant Sciences, Tel Aviv University, Tel Aviv 69978, Israel.
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MeSH Terms
Arabidopsis / physiology
Guanine Nucleotide Exchange Factors / chemistry,  physiology*
Plant Physiological Phenomena*
Plant Proteins / chemistry,  physiology*
Signal Transduction
rho GTP-Binding Proteins / physiology*
Reg. No./Substance:
0/Guanine Nucleotide Exchange Factors; 0/Plant Proteins; EC GTP-Binding Proteins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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