Document Detail


Turning crocodilian hearts into bird hearts: growth rates are similar for alligators with and without right-to-left cardiac shunt.
MedLine Citation:
PMID:  20639429     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The functional and possible adaptive significance of non-avian reptiles' dual aortic arch system and the ability of all non-avian reptiles to perform central vascular cardiac shunts have been of great interest to comparative physiologists. The unique cardiac anatomy of crocodilians - a four-chambered heart with the dual aortic arch system - allows for only right-to-left (R-L; pulmonary bypass) cardiac shunt and for surgical elimination of this shunt. Surgical removal of the R-L shunt, by occluding the left aorta (LAo) upstream and downstream of the foramen of Panizza, results in a crocodilian with an obligatory, avian/mammalian central circulation. In this study, R-L cardiac shunt was eliminated in age-matched, female American alligators (Alligator mississippiensis; 5-7 months of age). We tested the hypothesis that surgical elimination of R-L cardiac shunt would impair growth (a readily measured proxy for fitness) compared with sham-operated, age-matched controls, especially in animals subjected to exhaustive exercise. While regular exercise caused a decrease in size (snout-to-vent length, head length and body mass), elimination of the capacity for R-L cardiac shunt did not greatly reduce animal growth, despite a chronic ventricular enlargement in surgically altered juvenile alligators. We speculate that, despite being slightly smaller, alligators with an occluded LAo would have reached sexual maturity in the same breeding season as control alligators. This study suggests that crocodilian R-L cardiac shunt does not provide an adaptive advantage for juvenile alligator growth and supports the logic that cardiac shunts persist in crocodilians because they have not been selected against.
Authors:
John Eme; June Gwalthney; Tomasz Owerkowicz; Jason M Blank; James W Hicks
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  The Journal of experimental biology     Volume:  213     ISSN:  1477-9145     ISO Abbreviation:  J. Exp. Biol.     Publication Date:  2010 Aug 
Date Detail:
Created Date:  2010-07-19     Completed Date:  2010-10-19     Revised Date:  2013-05-29    
Medline Journal Info:
Nlm Unique ID:  0243705     Medline TA:  J Exp Biol     Country:  England    
Other Details:
Languages:  eng     Pagination:  2673-80     Citation Subset:  IM    
Affiliation:
University of California, Irvine, Ecology and Evolutionary Biology, 321 Steinhaus Hall, Irvine, CA 92697-2525, USA. jeme@uci.edu
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MeSH Terms
Descriptor/Qualifier:
Alligators and Crocodiles / anatomy & histology*,  growth & development*,  physiology
Animals
Birds / anatomy & histology*,  physiology*
Body Weight / physiology
Cardiovascular Physiological Phenomena*
Coronary Circulation / physiology
Female
Heart / anatomy & histology*,  physiology*
Least-Squares Analysis
Grant Support
ID/Acronym/Agency:
2T32AR047752/AR/NIAMS NIH HHS
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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