Document Detail


Turcot's syndrome. A review.
MedLine Citation:
PMID:  2846249     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Turcot's syndrome represents the association between familial multiple polyposis coli and neural tumors. The syndrome is reviewed with reference to genetics, colonic and central nervous system manifestations. This evidence suggests that Turcot's syndrome represents one manifestation of the pleiotropic autosomal dominant gene responsible for familial polyposis coli and the associated extracolonic manifestations of Gardner's syndrome. A diagnosis of Turcot's syndrome should be restricted to those patients with familial polyposis coli associated with gliomas or medulloblastomas. A further case is presented that is believed to be the first report of such a case in the United Kingdom.
Authors:
L Jarvis; N Bathurst; D Mohan; D Beckly
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Diseases of the colon and rectum     Volume:  31     ISSN:  0012-3706     ISO Abbreviation:  Dis. Colon Rectum     Publication Date:  1988 Nov 
Date Detail:
Created Date:  1988-12-08     Completed Date:  1988-12-08     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0372764     Medline TA:  Dis Colon Rectum     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  907-14     Citation Subset:  IM    
Affiliation:
Department of Radiodiagnosis, Freedom Fields Hospital, Plymouth, Devon, United Kingdom.
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MeSH Terms
Descriptor/Qualifier:
Adenomatous Polyposis Coli / genetics*
Adult
Cerebellar Neoplasms / genetics*
Genes, Dominant
Humans
Male
Medulloblastoma / genetics*
Neoplasms, Multiple Primary / genetics*
Syndrome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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