Document Detail


Turcot syndrome: report of a case and review of the literature.
MedLine Citation:
PMID:  2540108     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We report a case of Turcot's syndrome in a 20-year old man with multiple adenomatous polyps of the colon and glioblastoma multiforme. Detailed histopathological study of all 25 polyps removed from his colon confirmed the distinct morphological and numerical features of the colonic polyposis in Turcot's syndrome. Moreover, 45% of the total polyps and all polyps with a diameter exceeding 2 cm showed malignant transformation, indicating the precancerous nature of these polyps. These findings are discussed together with data obtained from a literature review of 32 histopathologically confirmed cases of Turcot's syndrome with reference to the possible heterogeneous nature of the syndrome at the present time. The current views on the relationship of Turcot's syndrome to other polyposis coli syndromes are presented.
Authors:
Z A Jamjoom; S Sadiq; A B Mofti; I al-Mofleh; D Ajarim
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  International surgery     Volume:  74     ISSN:  0020-8868     ISO Abbreviation:  Int Surg     Publication Date:    1989 Jan-Mar
Date Detail:
Created Date:  1989-06-08     Completed Date:  1989-06-08     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0043524     Medline TA:  Int Surg     Country:  ITALY    
Other Details:
Languages:  eng     Pagination:  45-50     Citation Subset:  IM    
Affiliation:
Division of Neurosurgery, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
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MeSH Terms
Descriptor/Qualifier:
Adenomatous Polyposis Coli / pathology,  surgery*
Adult
Brain Neoplasms / surgery*
Glioblastoma / surgery*
Humans
Male
Syndrome

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