| Tumour cell death induced by the bulk photovoltaic effect of LiNbO(3):Fe under visible light irradiation. | |
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MedLine Citation:
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PMID: 21336376 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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This work reports a pioneer application of the bulk photovoltaic effect in the biomedical field. Massive necrotic cell death was induced in human tumour cell cultures grown on a bulk photovoltaic material (iron-doped lithium niobate, LiNbO(3):Fe) after irradiation with visible light. Lethal doses (≈100% cell death) were obtained with low-intensity visible light sources (10-100 mW cm(-2) irradiances) and short exposure times of the order of minutes. The wavelength dependence to induce the lethal effect observed is consistent with that corresponding to the bulk photovoltaic effect generation in LiNbO(3):Fe. Necrosis also occurred when cultured tumour cells were exposed to LiNbO(3):Fe microparticles and visible light. |
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Authors:
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Alfonso Blázquez-Castro; Juan C Stockert; Begoña López-Arias; Angeles Juarranz; Fernando Agulló-López; Angel García-Cabañes; Mercedes Carrascosa |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-2-19 |
Journal Detail:
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Title: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology Volume: - ISSN: 1474-9092 ISO Abbreviation: - Publication Date: 2011 Feb |
Date Detail:
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Created Date: 2011-2-21 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101124451 Medline TA: Photochem Photobiol Sci Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Departamento de Biología, Facultad de Ciencias, Universidad Autónoma de Madrid, 28049, Madrid, Spain. alfonso.blazquez@uam.es. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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