Document Detail

Tumour antigens associated with primary mediastinal choriocarcinoma.
MedLine Citation:
PMID:  73406     Owner:  NLM     Status:  MEDLINE    
Various biochemical markers of cancer were investigated in two men aged 26 and 45 years with primary mediastinal choriocarcinoma. The daily excretion of urinary human chorionic gonadotropin (HCG) and the serum concentration of the beta-subunit of HCG were elevated in both patients, but carcinoembryonic antigen, Regan isoenzyme, alpha1-fetoprotein, serum pregnancy-associated globulin and human chorionic somatomammotropin were not detectable. Comparison of the results of the investigation of biochemical markers of this rare neoplasm in these two men with those published previously illustrates the discordance in the expression of biochemical markers of primary mediastinal choriocarcinoma.
J C Forest; J Talbot; M Pagé; J M Loiselle
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Canadian Medical Association journal     Volume:  117     ISSN:  0008-4409     ISO Abbreviation:  Can Med Assoc J     Publication Date:  1977 Dec 
Date Detail:
Created Date:  1978-02-18     Completed Date:  1978-02-18     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0414110     Medline TA:  Can Med Assoc J     Country:  CANADA    
Other Details:
Languages:  eng     Pagination:  1386-8     Citation Subset:  AIM; IM    
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MeSH Terms
Alkaline Phosphatase / analysis
Antigens, Neoplasm / analysis*
Beta-Globulins / analysis
Carcinoembryonic Antigen / analysis
Choriocarcinoma / immunology*
Chorionic Gonadotropin / blood,  urine
Isoenzymes / analysis
Mediastinal Neoplasms / immunology*
Middle Aged
Placental Lactogen / analysis
alpha-Fetoproteins / analysis
Reg. No./Substance:
0/Antigens, Neoplasm; 0/Beta-Globulins; 0/Carcinoembryonic Antigen; 0/Chorionic Gonadotropin; 0/Isoenzymes; 0/alpha-Fetoproteins; 9035-54-5/Placental Lactogen; EC Phosphatase

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