Document Detail

Tumour necrosis factor in the canine endometrium: an immunohistochemical study.
MedLine Citation:
PMID:  20880318     Owner:  NLM     Status:  In-Data-Review    
Tumour necrosis factor (TNF), a pleiotropic cytokine that regulates cell growth and differentiation as well as the synthesis of other cytokines, has been identified in the uterus of several species describing a cyclic pattern, eventually under ovarian steroid regulation. Information is yet limited on the presence of TNF protein in the canine endometrium during the oestrous cycle and early pregnancy. This study depicts the temporal immunolocalization of TNF in the bitch endometrium along the oestrous cycle and changes associated with the early steps of embryo invasion. TNF immunolabelling was found in both the stromal fibroblasts and epithelial components of the canine endometrium in all stages studied. Stromal immunostaining was more intense than that of the epithelia, in all the stages of the oestrous cycle. In addition, a tendency for a decrease in the surface epithelium intensity score was found in early dioestrus. A positive glandular content was only observed in anoestrus and proestrus stages. In early pregnancy (days 13-16), TNF immunolabelling was detected at the embryo-maternal surface, in the syncytium cords and the trophoblast, as well in the endometrial stroma and the basal endometrial glands, but not in the lacunar epithelium. The overall TNF immunoreactivity was higher in early pregnancy samples in comparison with those of the early dioestrus and dioestrus stages, suggesting it plays a role during implantation.
R Payan-Carreira; Ma Pires; B Ström Holst; H Rodriguez-Martinez
Related Documents :
18491238 - Placental activin a is required for follicular development during the second half of pr...
7444998 - Serum progesterone and corpus luteum function in pregnant pigtailed monkeys (macaca nem...
8040838 - Immunocytochemical localization of nonluteal ovarian relaxin.
11030228 - Early diagnosis of pregnancy in sows by ultrasound evaluation of embryo development and...
17055308 - Alterations in the maternal peripheral microvascular response in pregnancies complicate...
9508038 - Semicircadian rhythms of c-fos expression in several hypothalamic areas during pregnanc...
Publication Detail:
Type:  Journal Article     Date:  2010-09-29
Journal Detail:
Title:  Reproduction in domestic animals = Zuchthygiene     Volume:  46     ISSN:  1439-0531     ISO Abbreviation:  Reprod. Domest. Anim.     Publication Date:  2011 Jun 
Date Detail:
Created Date:  2011-05-06     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9015668     Medline TA:  Reprod Domest Anim     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  410-8     Citation Subset:  IM    
Copyright Information:
© 2010 Blackwell Verlag GmbH.
CECAV, University of Trás-os-Montes and Alto Douro, Vila Real, Portugal SLU, Department of Clinical Sciences, Uppsala Department of Clinical and Experimental Medicine, Faculty of Health Sciences, Linköping University, Linköping, Sweden.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Chronic treatment with melatonin stimulates dendrite maturation and complexity in adult hippocampal ...
Next Document:  Gray matter lesions in Nasu-Hakola disease: a report on three autopsy cases.