| Tumor oximetry: comparison of 19F MR EPI and electrodes. | |
| | |
MedLine Citation:
|
PMID: 14562701 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
We recently described a novel approach to measuring regional tumor oxygen tension. This approach is based on 19F pulse burst saturation recovery NMR echo planar imaging relaxometry of hexafluorobenzene or "FREDOM" (Fluorocarbon Relaxometry using Echo planar imaging for Dynamic Oxygen Mapping). We have now compared oxygen tension measurements using FREDOM with a traditional polarographic method (the Eppendorf Histograph) in a group of size matched Dunning prostate rat tumors R3327-AT1. We also compare MR and electrode approaches to monitoring dynamic changes with respect to interventions and demonstrate extension of the MR technique to rat breast tumors. |
| | |
Authors:
|
Ralph P Mason; Sandeep Hunjan; Anca Constantinescu; Yulin Song; Dawen Zhao; Eric W Hahn; Peter P Antich; Peter Peschke |
Publication Detail:
|
Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
|
Title: Advances in experimental medicine and biology Volume: 530 ISSN: 0065-2598 ISO Abbreviation: Adv. Exp. Med. Biol. Publication Date: 2003 |
Date Detail:
|
Created Date: 2003-10-17 Completed Date: 2003-11-20 Revised Date: 2007-11-14 |
Medline Journal Info:
|
Nlm Unique ID: 0121103 Medline TA: Adv Exp Med Biol Country: United States |
Other Details:
|
Languages: eng Pagination: 19-27 Citation Subset: IM |
Affiliation:
|
U.T. Southwestern Medical Center, Dallas, TX 75390, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adenocarcinoma
/
metabolism* Animals Electrodes* Fluorine Magnetic Resonance Imaging / methods* Male Oximetry / instrumentation, methods* Prostatic Neoplasms / metabolism* Rats |
| Grant Support | |
ID/Acronym/Agency:
|
R01 79515//PHS HHS |
| Chemical | |
Reg. No./Substance:
|
7782-41-4/Fluorine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Quantitative brain tissue oximetry, phase spectroscopy and imaging the range of homeostasis in pigle...
Next Document: Mapping cerebral glutamate 13C turnover and oxygen consumption by in vivo NMR.