Document Detail

Tumor-like coronary atheroma: a modern coronary evaluation with a historical perspective.
MedLine Citation:
PMID:  21720471     Owner:  NLM     Status:  MEDLINE    
The concept that atherosclerotic disease could be a form of neoplasm has been proposed in the medical literature for centuries, yet few modern cardiologists or pathologists describe atherosclerotic plaques as having the appearance of tumors. Although atherosclerosis is now considered to be an inflammatory disease, parallels between the pathophysiologic courses of atherosclerosis and neoplasia have been described since the 19th century. Current research is increasingly focused on mechanisms common to both diseases.Herein, we present the case of a 70-year-old man with a tumor-like coronary atheroma that was diagnosed on computed tomographic coronary angiography and confirmed with the use of intravascular ultrasound. However, the large plaque was not apparent on conventional invasive angiography. This case serves as a reminder of the limitations of invasive angiography and of the superiority of both computed tomographic coronary angiography and intravascular ultrasound in identifying and quantifying coronary plaque. We discuss our interpretation of the patient's lesion and review various theories of atherogenesis.
Brian G Schwartz; Jeffrey M Schussler; Robert L Rosenthal
Publication Detail:
Type:  Case Reports; Historical Article; Journal Article; Review    
Journal Detail:
Title:  Texas Heart Institute journal / from the Texas Heart Institute of St. Luke's Episcopal Hospital, Texas Children's Hospital     Volume:  38     ISSN:  1526-6702     ISO Abbreviation:  Tex Heart Inst J     Publication Date:  2011  
Date Detail:
Created Date:  2011-07-01     Completed Date:  2011-10-31     Revised Date:  2013-06-28    
Medline Journal Info:
Nlm Unique ID:  8214622     Medline TA:  Tex Heart Inst J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  275-8     Citation Subset:  IM    
Department of Cardiovascular Disease, Hamilton Heart & Vascular Hospital, Baylor University Medical Center, Dallas, Texas 75214, USA.
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MeSH Terms
Angioplasty, Balloon, Coronary / instrumentation
Coronary Angiography
Coronary Artery Disease / diagnosis*,  history,  therapy
Diagnosis, Differential
Diagnostic Imaging* / history,  methods
Heart Neoplasms / diagnosis*
History, 19th Century
History, 20th Century
Plaque, Atherosclerotic / diagnosis*,  history,  therapy
Predictive Value of Tests
Tomography, X-Ray Computed
Treatment Outcome
Ultrasonography, Interventional

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