Document Detail


Tumor immunology and interferon.
MedLine Citation:
PMID:  362539     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Host defense mechanisms against cancer depend on an intact cellular immunity system. Immunosurveillance depends on thymus lymphocytes which, when sensitized, form lymphokines. One of the important lymphokines produced by T-lymphocytes is called interferon, well known for its antiviral effects. Recent experimental evidence points also to the potential effectiveness of interferon against malignancies. Interferon and interferon-inducers have been found to alter the course of solid tumors, leukemia, sarcomas and lymphomas in experimental animals, possibly by stimulating the reticuloendothelial system to produce tumor rejection or by altering the surface of cells to change tumor and host reactions.
Authors:
B Feinerman
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Southern medical journal     Volume:  71     ISSN:  0038-4348     ISO Abbreviation:  South. Med. J.     Publication Date:  1978 Nov 
Date Detail:
Created Date:  1979-01-15     Completed Date:  1979-01-15     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0404522     Medline TA:  South Med J     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1409-11     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Humans
Immunity, Cellular
Interferons* / biosynthesis,  isolation & purification,  pharmacology
Leukemia, Experimental / drug therapy
Neoplasms / drug therapy,  immunology*
Neoplasms, Experimental / drug therapy
RNA, Viral / biosynthesis
T-Lymphocytes / metabolism
Virus Replication / drug effects
Viruses / drug effects,  metabolism
Chemical
Reg. No./Substance:
0/RNA, Viral; 9008-11-1/Interferons

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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