Document Detail

Tumor immunology and interferon.
MedLine Citation:
PMID:  362539     Owner:  NLM     Status:  MEDLINE    
Host defense mechanisms against cancer depend on an intact cellular immunity system. Immunosurveillance depends on thymus lymphocytes which, when sensitized, form lymphokines. One of the important lymphokines produced by T-lymphocytes is called interferon, well known for its antiviral effects. Recent experimental evidence points also to the potential effectiveness of interferon against malignancies. Interferon and interferon-inducers have been found to alter the course of solid tumors, leukemia, sarcomas and lymphomas in experimental animals, possibly by stimulating the reticuloendothelial system to produce tumor rejection or by altering the surface of cells to change tumor and host reactions.
B Feinerman
Related Documents :
3142009 - Effect of alpha- and gamma-interferon and tumor necrosis factor on colony formation of ...
17911639 - The heat shock protein hsp70 promotes mouse nk cell activity against tumors that expres...
8306339 - Effect of human natural killer cells on the metastatic growth of human melanoma xenogra...
17699849 - Ini1 induces interferon signaling and spindle checkpoint in rhabdoid tumors.
2459829 - In vitro antiproliferative efficacy of interferon-alpha, -gamma and tumor necrosis fact...
2624609 - Activation of natural killer cell cytotoxicity of human blood monocytes by a low molecu...
15662539 - Gene expression profiling: cell cycle deregulation and aneuploidy do not cause breast c...
15753399 - Inactivation of the mitogen-activated protein kinase pathway as a potential target-base...
23274849 - Osteoblastoma of the rib: a rare benign tumor with an unusual location.
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Southern medical journal     Volume:  71     ISSN:  0038-4348     ISO Abbreviation:  South. Med. J.     Publication Date:  1978 Nov 
Date Detail:
Created Date:  1979-01-15     Completed Date:  1979-01-15     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0404522     Medline TA:  South Med J     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1409-11     Citation Subset:  AIM; IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Immunity, Cellular
Interferons* / biosynthesis,  isolation & purification,  pharmacology
Leukemia, Experimental / drug therapy
Neoplasms / drug therapy,  immunology*
Neoplasms, Experimental / drug therapy
RNA, Viral / biosynthesis
T-Lymphocytes / metabolism
Virus Replication / drug effects
Viruses / drug effects,  metabolism
Reg. No./Substance:
0/RNA, Viral; 9008-11-1/Interferons

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Respirator paradox.
Next Document:  Adult respiratory distress syndrome.