| Tubulointerstitial nephritis and uveitis: report of a rare syndrome. | |
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MedLine Citation:
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PMID: 21189439 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Tubulointerstitial nephritis and uveitis (TINU) is a rare syndrome with unknown pathogenesis. Data have shown a higher prevalence in female gender. We present a man with tubulointerstitial nephritis and uveitis syndrome and antitubular antibody. A 23-year-old man presented with a history of weight loss, nausea, and vomiting, and uveitis. His serum creatinine was 2.1mg/d with pyuria and proteinuria in urinalysis. Other laboratory and imaging studies were unremarkable. Kidney biopsy showed granulomatous interstitial nephritis. Normal renal tissue specimen treated with patient's serum showed focal cytoplasmic staining in cortical tubular cells. The patient received prednisolone for 1 month. Interstitial nephritis and uveitis were well controlled. There was no recurrence in 1-year follow-up. We suggest that tubulointerstitial nephritis and uveitis syndrome should be considered in differential diagnosis of patients with interstitial nephritis and uveitis. Antitubular antibody may be used as a diagnosis marker for this syndrome. |
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Authors:
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Shokoufeh Savaj; Mojgan Asgari |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Iranian journal of kidney diseases Volume: 5 ISSN: 1735-8582 ISO Abbreviation: Iran J Kidney Dis Publication Date: 2011 Jan |
Date Detail:
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Created Date: 2010-12-29 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101316967 Medline TA: Iran J Kidney Dis Country: Iran |
Other Details:
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Languages: eng Pagination: 66-8 Citation Subset: IM |
Affiliation:
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Tehran University of Medical Sciences, Tehran, Iran. ssavaj@hotmail.com. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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