Document Detail

Tubular function impairment in patients with asymptomatic hyperuricemia.
MedLine Citation:
PMID:  926261     Owner:  NLM     Status:  MEDLINE    
Renal function studies were done on asymptomatic hyperuricemic subjects and normouricemic controls matched as to age, sex and blood pressure. Abnormal urinary sediments and proteinuria were found more frequently in asymptomatic hyperuricemic subjects than in the controls. In addition, the maximal osmolar concentrating ability of urine was markedly reduced in the asymptomatic hyperuricemic subjects. There was no difference in renal function measured by phenolsulfonphthalein excretion between the groups. Our results suggest that hyperuricemia alone may contribute to renal tubular impairment.
Y Nishida; E Yano; N Kamatani; I Akaoka
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of urology     Volume:  118     ISSN:  0022-5347     ISO Abbreviation:  J. Urol.     Publication Date:  1977 Dec 
Date Detail:
Created Date:  1978-01-27     Completed Date:  1978-01-27     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0376374     Medline TA:  J Urol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  908-9     Citation Subset:  AIM; IM    
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MeSH Terms
Kidney Diseases / etiology
Kidney Tubules / physiopathology*
Middle Aged
Phenolsulfonphthalein / diagnostic use
Uric Acid / blood*
Reg. No./Substance:
143-74-8/Phenolsulfonphthalein; 69-93-2/Uric Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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