Document Detail


Tuberculous radiculomyelitis complicating tuberculous meningitis: case report and review.
MedLine Citation:
PMID:  10854362     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Tuberculous radiculomyelitis (TBRM) is a complication of tuberculous meningitis (TBM), which has been reported rarely in the modern medical literature. We describe a case of TBRM that developed in an human immunodeficiency virus (HIV)-infected patient, despite prompt antituberculous treatment. To our knowledge, this is the second case of TBRM reported in an HIV-infected patient. We also review 74 previously reported cases of TBRM. TBRM develops at various periods after TBM, even in adequately treated patients after sterilization of the cerebrospinal fluid (CSF). The most common symptoms are subacute paraparesis, radicular pain, bladder disturbance, and subsequent paralysis. CSF evaluation usually shows an active inflammatory response with a very high protein level. MRI and CT scan are critical for diagnosis, revealing loculation and obliteration of the subarachnoid space along with linear intradural enhancement. As in other forms of paradoxical reactions to antituberculous treatment, there is evidence that steroid treatment might have a beneficial effect.
Authors:
S Hernández-Albújar; J R Arribas; A Royo; J J González-García; J M Peña; J J Vázquez
Publication Detail:
Type:  Case Reports; Journal Article; Review     Date:  2000-06-14
Journal Detail:
Title:  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America     Volume:  30     ISSN:  1058-4838     ISO Abbreviation:  Clin. Infect. Dis.     Publication Date:  2000 Jun 
Date Detail:
Created Date:  2000-09-12     Completed Date:  2000-09-12     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  9203213     Medline TA:  Clin Infect Dis     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  915-21     Citation Subset:  IM; X    
Affiliation:
Servicio de Medicina Interna (Unidad VIH), Hospital Universitario "La Paz," Facultad de Medicina Universidad Autónoma de Madrid, 28046 Madrid, Spain.
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MeSH Terms
Descriptor/Qualifier:
AIDS-Related Opportunistic Infections*
Adolescent
Adult
Aged
Female
Humans
Magnetic Resonance Imaging
Male
Middle Aged
Myelitis / etiology*,  radiography
Radiculopathy / etiology*,  radiography
Spinal Cord / radiography
Tuberculosis, Meningeal / complications*

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