| Tuberculous pulmonary gangrene: report of a case and review. | |
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MedLine Citation:
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PMID: 8161634 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Pulmonary gangrene is an uncommon but life-threatening complication of bacterial pneumonia. Only four cases of pulmonary gangrene due to Mycobacterium tuberculosis have been described to date; another case of pulmonary gangrene was attributed to unidentified mycobacteria. We report a fetal case of tuberculous pulmonary gangrene (TPG) and review the literature on this infection. To our knowledge this is the first case of TPG documented by thoracic computed tomographic scanning. Radiological features of pulmonary gangrene are distinctive, and identification of pulmonary parenchyma in the mass on computed tomography may be considered as pathognomonic. Analysis of the six cases revealed that most of the patients were aged, and one-half of them were alcohol abusers. Right-upper-lobe involvement predominated. When performed, sputum smears disclosed acid-fast bacilli. M. tuberculosis was cultured from sputum or pathologic material in five of the six cases. Four patients (66.7%) died. Four of six patients with TPG received antituberculous therapy, and two of them survived; no patient underwent surgical intervention. Although surgical management has been successfully employed in cases of bacterial pulmonary gangrene, TPG has always been treated with medical therapy alone. In spite of administration of antituberculous therapy, mortality is high. |
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Authors:
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J López-Contreras; J Ris; P Domingo; M Puig; E Martínez |
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Publication Detail:
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Type: Case Reports; Journal Article; Review |
Journal Detail:
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Title: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America Volume: 18 ISSN: 1058-4838 ISO Abbreviation: Clin. Infect. Dis. Publication Date: 1994 Feb |
Date Detail:
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Created Date: 1994-05-26 Completed Date: 1994-05-26 Revised Date: 2005-11-16 |
Medline Journal Info:
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Nlm Unique ID: 9203213 Medline TA: Clin Infect Dis Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 243-5 Citation Subset: IM |
Affiliation:
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Department of Internal Medicine, Hospital de la Santa Creu i Sant Pau, Universitat Autonoma de Barcelona, Spain. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Alcoholism
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complications Gangrene / etiology*, radiography, therapy Humans Male Middle Aged Tomography, X-Ray Computed Tuberculosis, Pulmonary / complications*, radiography |
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